Ivo Guber1,2, Ciara Bergin3, Shruti Malde4, Josef Guber5, Samer Hamada4, Damian Lake4. 1. Queen Victoria Hospital, NHS Foundation Trust, East Grinstead, West Sussex, UK. ivo.guber@augenchirurgie.ch. 2. Department of Ophthalmology, University of Geneva, Rue de Alcide-Jentzer 22, 1205, Geneva, Switzerland. ivo.guber@augenchirurgie.ch. 3. Jules-Gonin Eye Hospital, University of Lausanne, Lausanne, Switzerland. 4. Queen Victoria Hospital, NHS Foundation Trust, East Grinstead, West Sussex, UK. 5. Department of Ophthalmology, University of Basel, Basel, Switzerland.
Abstract
BACKGROUND: To investigate response of dissolving collagen contact lenses as an alternative for bandage contact lenses, for the post-interventional care of epithelial defects after corneal cross-linking (CXL) treatment for keratoconus. PATIENTS AND METHODS: Follow-up visits were performed at day 1, 4 and 1 month after the intervention. We reviewed notes for re-epithelialization, comfort/pain and any untoward effects of Collagen SOFT SHIELD®. Assessment included visual acuity (VA), refraction (SE); corneal haze, epithelial erosion and pain status were assessed subjectively on a 4-point scale, from 0 (none) to 3 (severe). RESULTS: Thirty consecutive CXL patients with collagen shield application after CXL were included. Mean age was 28 years (range from 16 to 51 years old). Pre-CXL VA was 0.7 logMAR IQR 0.4-1.0; post-CXL VA at day 4 and month 1 was 0.6 logMAR IQR 0.4-0.9. Post-operative mean SE was 5.5D ± 4.1D. In all patients, the Collagen SOFT SHIELD® was completely dissolved at the 4-day follow-up visit. In most cases, epithelial defect was closed at day 4, on average 0.8 ± 0.5 days post-intervention; all epithelial defects were closed by month 1. Haze was minimal (mean haze score 1.4 ± 0.7 at day 4 and 1.0 ± 0.6 at 1 month). No adverse effects such as infection were observed. CONCLUSIONS: This study indicates that Oasis Collagen SOFT SHIELD® is valuable and safe alternative to standard bandage contact lens for the treatment of epithelial defects. This outcome may be of particular interest in patients where the contact lens removal is likely to be problematic.
BACKGROUND: To investigate response of dissolving collagen contact lenses as an alternative for bandage contact lenses, for the post-interventional care of epithelial defects after corneal cross-linking (CXL) treatment for keratoconus. PATIENTS AND METHODS: Follow-up visits were performed at day 1, 4 and 1 month after the intervention. We reviewed notes for re-epithelialization, comfort/pain and any untoward effects of Collagen SOFT SHIELD®. Assessment included visual acuity (VA), refraction (SE); corneal haze, epithelial erosion and pain status were assessed subjectively on a 4-point scale, from 0 (none) to 3 (severe). RESULTS: Thirty consecutive CXL patients with collagen shield application after CXL were included. Mean age was 28 years (range from 16 to 51 years old). Pre-CXL VA was 0.7 logMAR IQR 0.4-1.0; post-CXL VA at day 4 and month 1 was 0.6 logMAR IQR 0.4-0.9. Post-operative mean SE was 5.5D ± 4.1D. In all patients, the Collagen SOFT SHIELD® was completely dissolved at the 4-day follow-up visit. In most cases, epithelial defect was closed at day 4, on average 0.8 ± 0.5 days post-intervention; all epithelial defects were closed by month 1. Haze was minimal (mean haze score 1.4 ± 0.7 at day 4 and 1.0 ± 0.6 at 1 month). No adverse effects such as infection were observed. CONCLUSIONS: This study indicates that Oasis Collagen SOFT SHIELD® is valuable and safe alternative to standard bandage contact lens for the treatment of epithelial defects. This outcome may be of particular interest in patients where the contact lens removal is likely to be problematic.
Authors: Siwei Zhou; Kristin M Hunt; Arman S Grewal; Kimberly M Brothers; Deepinder K Dhaliwal; Robert M Q Shanks Journal: Eye Contact Lens Date: 2018-11 Impact factor: 2.018
Authors: Ivo Guber; Josef Guber; Claude Kaufmann; Lucas M Bachmann; Michael A Thiel Journal: Graefes Arch Clin Exp Ophthalmol Date: 2012-08-16 Impact factor: 3.117