Literature DB >> 3065646

[New results on the linearity of the dose-response relationship of radiation-induced mutation].

H Traut1.   

Abstract

Mutations induced by ionizing radiation in germ cells may affect future generations; mutations induced in somatic cells may damage the irradiated persons themselves, because radiation carcinogenesis is assumed to result from genetic damage induced in somatic cells. Since we are exposed mainly to low doses of ionizing radiation, both from natural and artificial sources, especially the dose dependence of radiation-induced mutations in the low-dose range is of interest. A review of recent studies on the induction of mutations by X-rays in human cells (in vitro) favors the hypothesis that in the low-dose range the dose dependence is linear, without a "threshold."

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Year:  1988        PMID: 3065646     DOI: 10.1007/bf00377813

Source DB:  PubMed          Journal:  Naturwissenschaften        ISSN: 0028-1042


  11 in total

1.  MUTATION RATES OF LOW DOSE LEVEL IN DROSOPHILA MELANOGASTER.

Authors:  T SHIOMI; E INAGAKI; H INAGAKI; Y NAKAO
Journal:  J Radiat Res       Date:  1963 Jun-Dec       Impact factor: 2.724

2.  Frequencies of chromosomal aberrations induced in human blood lymphocytes by low doses of X-rays.

Authors:  D C Lloyd; A A Edwards; A Léonard; G Deknudt; A Natarajan; G Obe; F Palitti; C Tanzarella; E J Tawn
Journal:  Int J Radiat Biol Relat Stud Phys Chem Med       Date:  1988-01

3.  Atomic bomb doses reassessed.

Authors:  L Roberts
Journal:  Science       Date:  1987-12-18       Impact factor: 47.728

4.  Evidence for linear response for the induction of mutations in human cells by x-ray exposures below 10 rads.

Authors:  A J Grosovsky; J B Little
Journal:  Proc Natl Acad Sci U S A       Date:  1985-04       Impact factor: 11.205

5.  Direct analysis of radiation-induced chromosome fragments and rings in unstimulated human peripheral blood lymphocytes by means of the premature chromosome condensation technique.

Authors:  G E Pantelias; H D Maillie
Journal:  Mutat Res       Date:  1985-03       Impact factor: 2.433

6.  Do radiation-induced thioguanine-resistant mutants of cultured mammalian cells arise by HGPRT gene mutation or X-chromosome rearrangement?

Authors:  R Cox; W K Masson
Journal:  Nature       Date:  1978-12-07       Impact factor: 49.962

7.  Effect of low-dose acute X-irradiation on the frequencies of chromosomal aberrations in human peripheral lymphocytes in vitro.

Authors:  J Pohl-Rüling; P Fischer; O Haas; G Obe; A T Natarajan; P P van Buul; K E Buckton; N O Bianchi; M Larramendy; M Kucerová; Z Poliková; A Leonard; L Fabry; F Palitti; T Sharma; W Binder; R N Mukherjee; U Mukherjee
Journal:  Mutat Res       Date:  1983 Jun-Jul       Impact factor: 2.433

8.  Measurement of mutagenesis in mammalian cells.

Authors:  C Waldren; C Jones; T T Puck
Journal:  Proc Natl Acad Sci U S A       Date:  1979-03       Impact factor: 11.205

9.  The incidence of unstable chromosome aberrations in peripheral blood lymphocytes from unirradiated and occupationally exposed people.

Authors:  D C Lloyd; R J Purrott; E J Reeder
Journal:  Mutat Res       Date:  1980-08       Impact factor: 2.433

10.  Measurement of low levels of x-ray mutagenesis in relation to human disease.

Authors:  C Waldren; L Correll; M A Sognier; T T Puck
Journal:  Proc Natl Acad Sci U S A       Date:  1986-07       Impact factor: 11.205

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