Literature DB >> 30655937

Inhibitors of G12C Mutant Ras Proteins for the Treatment of Cancers.

Robert B Kargbo1.   

Abstract

Entities:  

Year:  2018        PMID： 30655937      PMCID： PMC6331154          DOI： 10.1021/acsmedchemlett.8b00576

Source DB:  PubMed          Journal:  ACS Med Chem Lett        ISSN： 1948-5875            Impact factor:   4.345


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  5 in total

Review 1.  Colorectal cancer-derived exosomes and modulation KRAS signaling.

Authors:  Yan Hua Wan; Qi Sheng Liu; Sha Sha Wan; Ri Wei Wang
Journal:  Clin Transl Oncol       Date:  2022-07-05       Impact factor: 3.340

2.  Pharmacophoric analogs of sotorasib-entrapped KRAS G12C in its inactive GDP-bound conformation: covalent docking and molecular dynamics investigations.

Authors:  Abdul-Quddus Kehinde Oyedele; Abdeen Tunde Ogunlana; Ibrahim Damilare Boyenle; Najahtulahi Opeyemi Ibrahim; Ibrahim Olajide Gbadebo; Nurudeen Abiodun Owolabi; Ashiru Mojeed Ayoola; Ann Christopher Francis; Olajumoke Habeebah Eyinade; Temitope Isaac Adelusi
Journal:  Mol Divers       Date:  2022-10-21       Impact factor: 3.364

Review 3.  Therapeutic advances in metastatic pancreatic cancer: a focus on targeted therapies.

Authors:  Anthony Turpin; Cindy Neuzillet; Elise Colle; Nelson Dusetti; Rémy Nicolle; Jérôme Cros; Louis de Mestier; Jean-Baptiste Bachet; Pascal Hammel
Journal:  Ther Adv Med Oncol       Date:  2022-09-06       Impact factor: 5.485

4.  Mechanistic insights into the clinical Y96D mutation with acquired resistance to AMG510 in the KRASG12C.

Authors:  Haiming Zhuang; Jigang Fan; Mingyu Li; Hao Zhang; Xiuyan Yang; Ligen Lin; Shaoyong Lu; Qing Wang; Yaqin Liu
Journal:  Front Oncol       Date:  2022-08-10       Impact factor: 5.738

5.  KRASG12C Inhibition with Sotorasib in Advanced Solid Tumors.

Authors:  David S Hong; Marwan G Fakih; John H Strickler; Jayesh Desai; Gregory A Durm; Geoffrey I Shapiro; Gerald S Falchook; Timothy J Price; Adrian Sacher; Crystal S Denlinger; Yung-Jue Bang; Grace K Dy; John C Krauss; Yasutoshi Kuboki; James C Kuo; Andrew L Coveler; Keunchil Park; Tae Won Kim; Fabrice Barlesi; Pamela N Munster; Suresh S Ramalingam; Timothy F Burns; Funda Meric-Bernstam; Haby Henary; Jude Ngang; Gataree Ngarmchamnanrith; June Kim; Brett E Houk; Jude Canon; J Russell Lipford; Gregory Friberg; Piro Lito; Ramaswamy Govindan; Bob T Li
Journal:  N Engl J Med       Date:  2020-09-20       Impact factor: 176.079
  5 in total

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