| Literature DB >> 3065264 |
F S Tanzer1, E Tolun, G H Fridland, C Dass, J Killmar, P W Tinsley, D M Desiderio.
Abstract
The presence of the free opioid pentapeptide methionine enkephalin (ME) and of ME-containing peptide(s) was established firmly in decalcified, depulped human teeth by using a combination of methods including RP-HPLC, radioimmunoassay, radioreceptorassay, trypsin, carboxypeptidase B, fast atom bombardment mass spectrometry, and MS/MS methodology. Positive structural identification of ME was made with mass spectrometry. Those data demonstrate the presence of the preproenkephalinergic A system in the human trigeminal sensory termini.Entities:
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Year: 1988 PMID： 3065264 DOI： 10.1111/j.1399-3011.1988.tb00671.x
Source DB: PubMed Journal: Int J Pept Protein Res ISSN： 0367-8377