Literature DB >> 30652549

An Approach to Identify Delivery of Palliative Radiation Therapy Using Health Care Claims Data: A Proof-of-Concept Application of a Visual Analytics Tool.

Eberechukwu Onukwugha1, Jinani Jayasekera1, James Gardner1, Sana Malik1, C Daniel Mullins1, Arif Hussain1, Jay P Ciezki1, Chandana A Reddy1, Brian Seal1, Adriana Valderrama1, Young Kwok1.   

Abstract

PURPOSE: There is limited information on the use of data visualization tools for health services research applications. We provide a proof-of-concept application that focuses on claims-based measures of palliative radiation therapy. We investigate whether a guided, data-driven investigation contributes information for subsequent statistical analysis and algorithm development.
METHODS: This retrospective cohort study used linked registry and claims data on men who were diagnosed with stage IV M0 or stage IV M1b prostate cancer between 2005 and 2009, with associated claims from 2005 through 2010, and receiving radiation therapy. Preprocessing of data was accomplished by using EventFlow software to investigate longitudinal patterns in claims for radiation therapy in the 13 months after cancer diagnosis. Guided by results from EventFlow, we developed descriptive statistics to investigate the length of radiation therapy, use of bone metastasis coding, and mortality between M1b and M0 patients.
RESULTS: A total of 1,151 patients met the inclusion criteria. Taking advantage of the novel aggregation capability of EventFlow, we observed differences in the length of radiation therapy and the use of bone metastasis coding between men with (M1b) and without (M0) a diagnosis of bone metastasis. Seventy-nine percent of M1b patients received radiation for a duration ≤ 4 weeks, which suggested palliative radiation (to the bone). Seventy-six percent of M0 patients received radiation for ≥ 6 weeks, which suggested radiation to the prostate. Mortality was higher among those who received a shorter duration of radiation therapy compared with those who received a longer duration of therapy.
CONCLUSION: Use of EventFlow, followed by statistical analysis of the linked registry and claims data, identified useful components of a claims-based measure of radiation to the bone.

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Year:  2018        PMID: 30652549      PMCID: PMC7010427          DOI: 10.1200/CCI.17.00075

Source DB:  PubMed          Journal:  JCO Clin Cancer Inform        ISSN: 2473-4276


  13 in total

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2.  Prostate cancer incidence and mortality trends in 37 European countries: an overview.

Authors:  F Bray; J Lortet-Tieulent; J Ferlay; D Forman; A Auvinen
Journal:  Eur J Cancer       Date:  2010-11       Impact factor: 9.162

3.  Screening with prostate specific antigen and metastatic prostate cancer risk: a population based case-control study.

Authors:  Jacek A Kopec; Vivek Goel; Peter S Bunting; Jan Neuman; Eric C Sayre; Padraig Warde; Peter Levers; Neil Fleshner
Journal:  J Urol       Date:  2005-08       Impact factor: 7.450

4.  Mortality following bone metastasis and skeletal-related events among men with prostate cancer: a population-based analysis of US Medicare beneficiaries, 1999-2006.

Authors:  N Sathiakumar; E Delzell; M A Morrisey; C Falkson; M Yong; V Chia; J Blackburn; T Arora; M L Kilgore
Journal:  Prostate Cancer Prostatic Dis       Date:  2011-03-15       Impact factor: 5.554

5.  Validating billing/encounter codes as indicators of lung, colorectal, breast, and prostate cancer recurrence using 2 large contemporary cohorts.

Authors:  Michael J Hassett; Debra P Ritzwoller; Nathan Taback; Nikki Carroll; Angel M Cronin; Gladys V Ting; Deb Schrag; Joan L Warren; Mark C Hornbrook; Jane C Weeks
Journal:  Med Care       Date:  2014-10       Impact factor: 2.983

6.  The cost of treating skeletal-related events in patients with prostate cancer.

Authors:  Maureen J Lage; Beth L Barber; David J Harrison; Sun Jun
Journal:  Am J Manag Care       Date:  2008-05       Impact factor: 2.229

7.  Variation in the Cost of Radiation Therapy Among Medicare Patients With Cancer.

Authors:  Anthony J Paravati; Isabel J Boero; Daniel P Triplett; Lindsay Hwang; Rayna K Matsuno; Beibei Xu; Loren K Mell; James D Murphy
Journal:  J Oncol Pract       Date:  2015-08-11       Impact factor: 3.840

8.  Longitudinal Trends in Costs of Palliative Radiation for Metastatic Prostate Cancer.

Authors:  Timothy J Robinson; Michaela A Dinan; Yanhong Li; W Robert Lee; Shelby D Reed
Journal:  J Palliat Med       Date:  2015-08-04       Impact factor: 2.947

Review 9.  Clinical and economic burden of bone metastasis and skeletal-related events in prostate cancer.

Authors:  Candice Yong; Eberechukwu Onukwugha; C Daniel Mullins
Journal:  Curr Opin Oncol       Date:  2014-05       Impact factor: 3.645

10.  Palliative radiation therapy in patients with metastasized pancreatic cancer - description of a rare patient group.

Authors:  Daniel Habermehl; Ingo C Brecht; Jürgen Debus; Stephanie E Combs
Journal:  Eur J Med Res       Date:  2014-05-13       Impact factor: 2.175

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