Literature DB >> 3065122

[Gastric adenocarcinoma surgically treated. A multivariate analysis of prognostic factors].

D Elias1, P H Lasser, C Bognel, J M Nadal, K Rahal, R Pineda, P Rougier.   

Abstract

One hundred and twelve curatively resected gastric adenocarcinomas were studied retrospectively to appreciate the survival factors. Twenty different criteria (clinic, histologic and therapeutic parameters) were assessed using univariate and then multivariate analysis (semi parametric regression (COX's) model). Only three criteria were very important according to the multivariate analysis: 1) invasion of neighboring organs (p less than 0.006) with a relative risk score (RRS) of 4.26; 2) intravascular or intralymphatic tumor embols outside the tumor (p less than 0.004; RRS = 2.11); 3) invaded distal nodes (located at the origin of the vessels (p less than 0.04; RRS = 1.88). A prognosis index was described according to these results. A repartition of the patients in three prognostic groups according to these 3 criteria was proposed. Future, trials should consider these three different prognostic groups.

Entities:  

Mesh:

Year:  1988        PMID: 3065122

Source DB:  PubMed          Journal:  Gastroenterol Clin Biol        ISSN: 0399-8320


  3 in total

1.  Morphological predictors of survival in early and advanced gastric carcinoma.

Authors:  P Schmitz-Moormann; P Hermanek; G W Himmelmann
Journal:  J Cancer Res Clin Oncol       Date:  1992       Impact factor: 4.553

2.  Prognosis of gastric carcinoma after curative surgery. A population-based study using multivariate crude and relative survival analysis.

Authors:  P Arveux; J Faivre; M C Boutron; F Piard; L Dusserre-Guion; E Monnet; P Hillon
Journal:  Dig Dis Sci       Date:  1992-05       Impact factor: 3.199

3.  Pathological prognostic factors in the second British Stomach Cancer Group trial of adjuvant therapy in resectable gastric cancer.

Authors:  C C Yu; D A Levison; J A Dunn; L C Ward; M Demonakou; W H Allum; M T Hallisey
Journal:  Br J Cancer       Date:  1995-05       Impact factor: 7.640

  3 in total

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