Literature DB >> 30648432

Experimental free ligand conformations: a missing link in structure-based drug discovery.

Elisabetta Chiarparin1, Martin J Packer2, David M Wilson1.   

Abstract

Keywords:  NMR; free ligand conformations; medicinal chemistry; protein structure; structure-based drug discovery; x-ray

Mesh：

Substances：

Year:  2019        PMID： 30648432     DOI： 10.4155/fmc-2018-0339

Source DB:  PubMed          Journal:  Future Med Chem        ISSN： 1756-8919            Impact factor:   3.808


× No keyword cloud information.
  2 in total

Review 1.  NMR spectroscopy in drug discovery and development: Evaluation of physico-chemical properties.

Authors:  Mire Zloh
Journal:  ADMET DMPK       Date:  2019-12-11

2.  Relating Conformational Equilibria to Conformer-Specific Lipophilicities: New Opportunities in Drug Discovery.

Authors:  Bruno Linclau; Zhong Wang; Benjamin Jeffries; Jérôme Graton; Rodrigo J Carbajo; Davy Sinnaeve; Jean-Yves Le Questel; James S Scott; Elisabetta Chiarparin
Journal:  Angew Chem Int Ed Engl       Date:  2021-12-29       Impact factor: 16.823
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.