Literature DB >> 30645169

Variation in Serum PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9), Cardiovascular Disease Risk, and an Investigation of Potential Unanticipated Effects of PCSK9 Inhibition.

Ben M Brumpton1,2,3, Lars G Fritsche1,4, Jie Zheng2, Jonas Bille Nielsen5, Maria Mannila6,7, Ida Surakka5, Humaira Rasheed1,2, Gunnhild Åberge Vie1,8, Sarah E Graham5, Maiken Elvestad Gabrielsen1, Lars Erik Laugsand8,9,10, Pål Aukrust11,12,13, Lars Johan Vatten8, Jan Kristian Damås14,15, Thor Ueland11,16,17, Imre Janszky8, John-Anker Zwart18, Ferdinand M Van't Hooft7, Nabil Georges Seidah19, Kristian Hveem1, Cristen Willer4,5,20, George Davey Smith2, Bjørn Olav Åsvold1,21.   

Abstract

Entities:  

Keywords:  cardiovascular diseases; hospital records; lipids; lung; mental health; pain

Mesh：

Substances：

Year:  2019        PMID： 30645169      PMCID： PMC6530796          DOI： 10.1161/CIRCGEN.118.002335

Source DB:  PubMed          Journal:  Circ Genom Precis Med        ISSN： 2574-8300


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  5 in total

1.  The Swedish Twin Registry: establishment of a biobank and other recent developments.

Authors:  Patrik K E Magnusson; Catarina Almqvist; Iffat Rahman; Andrea Ganna; Alexander Viktorin; Hasse Walum; Linda Halldner; Sebastian Lundström; Fredrik Ullén; Niklas Långström; Henrik Larsson; Anastasia Nyman; Clara Hellner Gumpert; Maria Råstam; Henrik Anckarsäter; Sven Cnattingius; Magnus Johannesson; Erik Ingelsson; Lars Klareskog; Ulf de Faire; Nancy L Pedersen; Paul Lichtenstein
Journal:  Twin Res Hum Genet       Date:  2012-11-09       Impact factor: 1.587

2.  Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism.

Authors:  Marine Germain; Daniel I Chasman; Hugoline de Haan; Weihong Tang; Sara Lindström; Lu-Chen Weng; Mariza de Andrade; Marieke C H de Visser; Kerri L Wiggins; Pierre Suchon; Noémie Saut; David M Smadja; Grégoire Le Gal; Astrid van Hylckama Vlieg; Antonio Di Narzo; Ke Hao; Christopher P Nelson; Ares Rocanin-Arjo; Lasse Folkersen; Ramin Monajemi; Lynda M Rose; Jennifer A Brody; Eline Slagboom; Dylan Aïssi; France Gagnon; Jean-Francois Deleuze; Panos Deloukas; Christophe Tzourio; Jean-Francois Dartigues; Claudine Berr; Kent D Taylor; Mete Civelek; Per Eriksson; Bruce M Psaty; Jeanine Houwing-Duitermaat; Alison H Goodall; François Cambien; Peter Kraft; Philippe Amouyel; Nilesh J Samani; Saonli Basu; Paul M Ridker; Frits R Rosendaal; Christopher Kabrhel; Aaron R Folsom; John Heit; Pieter H Reitsma; David-Alexandre Trégouët; Nicholas L Smith; Pierre-Emmanuel Morange
Journal:  Am J Hum Genet       Date:  2015-03-12       Impact factor: 11.025

3.  The MR-Base platform supports systematic causal inference across the human phenome.

Authors:  Gibran Hemani; Jie Zheng; Benjamin Elsworth; Tom R Gaunt; Philip C Haycock; Kaitlin H Wade; Valeriia Haberland; Denis Baird; Charles Laurin; Stephen Burgess; Jack Bowden; Ryan Langdon; Vanessa Y Tan; James Yarmolinsky; Hashem A Shihab; Nicholas J Timpson; David M Evans; Caroline Relton; Richard M Martin; George Davey Smith
Journal:  Elife       Date:  2018-05-30       Impact factor: 8.140

4.  Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes.

Authors:  Brian A Ference; Jennifer G Robinson; Robert D Brook; Alberico L Catapano; M John Chapman; David R Neff; Szilard Voros; Robert P Giugliano; George Davey Smith; Sergio Fazio; Marc S Sabatine
Journal:  N Engl J Med       Date:  2016-12-01       Impact factor: 91.245

Review 5.  Circulating PCSK9 and Risk of Myocardial Infarction: The HUNT Study in Norway.

Authors:  Lars E Laugsand; Bjørn O Åsvold; Lars J Vatten; Imre Janszky; Carl G Platou; Annika E Michelsen; Jan K Damås; Pål Aukrust; Thor Ueland
Journal:  JACC Basic Transl Sci       Date:  2016-11-30
  5 in total

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