Literature DB >> 30643770

A Tale of Absent Crystalline Lens in an Eye with Retinoblastoma.

Aditya Bansal1, Veena Noronha1, Subramanian Krishnakumar1, Vikas Khetan1.   

Abstract

PURPOSE: To report the clinicopathological correlation of absent crystalline lens in an eye with retinoblastoma.
METHODS: A 1-year-old female child was brought to our patient services for pain and swelling in the right eye since the past few months. The child was diagnosed to have bilateral retinoblastoma and was suspected to have absence of crystalline lens in the right eye on the basis of clinical findings and ocular imaging. After 3 cycles of chemotherapy for suspected extraocular extension of tumor, she underwent enucleation. Absence of crystalline lens was confirmed on both gross and microscopic pathology.
RESULTS: We present a child with retinoblastoma, suspected to have absence of crystalline lens clinically and on ocular imaging (ultrasound and MRI), which was finally confirmed on ocular pathology examination post enucleation.
CONCLUSION: We report for the first time clinicopathologically proven absence of crystalline lens in an eye with retinoblastoma.

Entities:  

Keywords:  Aphakia; Lens involvement by tumor; Retinoblastoma

Year:  2018        PMID: 30643770      PMCID: PMC6322079          DOI: 10.1159/000484983

Source DB:  PubMed          Journal:  Ocul Oncol Pathol        ISSN: 2296-4657


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  1 in total

1.  Long noncoding RNA SNHG14 promotes the aggressiveness of retinoblastoma by sponging microRNA‑124 and thereby upregulating STAT3.

Authors:  Xiaowen Sun; Hui Shen; Shubin Liu; Jing Gao; Shuyan Zhang
Journal:  Int J Mol Med       Date:  2020-03-20       Impact factor: 4.101

  1 in total

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