AIM: We aimed to explore the prognostic implications of adiponectin (APN) levels in the serum and bronchoalveolar lavage (BAL) of patients with advanced NSCLC. MATERIALS & METHODS: 29 newly diagnosed patients with stage IV NSCLC were prospectively enrolled. Baseline serum and BAL levels of APN were assayed by ELISA and correlated with various clinicopathological parameters, including overall survival. RESULTS: No statistically significant correlations were observed between the serum or BAL levels of APN and the clinicopathological parameters evaluated. The only prognostic factor identified, both by univariate and multivariate survival analyses, was performance status. CONCLUSION: The results of our cohort failed to reveal any prognostic significance of serum and BAL levels of APN in stage IV NSCLC.
AIM: We aimed to explore the prognostic implications of adiponectin (APN) levels in the serum and bronchoalveolar lavage (BAL) of patients with advanced NSCLC. MATERIALS & METHODS: 29 newly diagnosed patients with stage IV NSCLC were prospectively enrolled. Baseline serum and BAL levels of APN were assayed by ELISA and correlated with various clinicopathological parameters, including overall survival. RESULTS: No statistically significant correlations were observed between the serum or BAL levels of APN and the clinicopathological parameters evaluated. The only prognostic factor identified, both by univariate and multivariate survival analyses, was performance status. CONCLUSION: The results of our cohort failed to reveal any prognostic significance of serum and BAL levels of APN in stage IV NSCLC.
Authors: Pamela T Soliman; Diana Wu; Guillermo Tortolero-Luna; Kathleen M Schmeler; Brian M Slomovitz; Molly S Bray; David M Gershenson; Karen H Lu Journal: Cancer Date: 2006-06-01 Impact factor: 6.860
Authors: Esther K Wei; Edward Giovannucci; Charles S Fuchs; Walter C Willett; Christos S Mantzoros Journal: J Natl Cancer Inst Date: 2005-11-16 Impact factor: 13.506
Authors: Ersilia Nigro; Fabio Perrotta; Maria Ludovica Monaco; Rita Polito; Pia Clara Pafundi; Maria Gabriella Matera; Aurora Daniele; Andrea Bianco Journal: Biomolecules Date: 2020-06-18