AIM: The frequency of pancreatic cancer in association with cancer of other organs ranges from 1 to 20%, with the most common ones being gastric, colon, thyroid and genitourinary. The presence of synchronous lung and pancreatic cancers is extremely rare. CASE SERIES: Two patients with extensive smoking history and variable presentations were found to have simultaneous lung and pancreatic masses both lesions being different histologically and on immunohistochemical staining. After individualized treatment plans, the first patient remains free of disease and the second patient is being treated with a palliative intent. CONCLUSION: The early recognition and treatment is important as there exists a significant survival difference in patients who have synchronous primaries as opposed to those with metastatic pancreatic adenocarcinoma.
AIM: The frequency of pancreatic cancer in association with cancer of other organs ranges from 1 to 20%, with the most common ones being gastric, colon, thyroid and genitourinary. The presence of synchronous lung and pancreatic cancers is extremely rare. CASE SERIES: Two patients with extensive smoking history and variable presentations were found to have simultaneous lung and pancreatic masses both lesions being different histologically and on immunohistochemical staining. After individualized treatment plans, the first patient remains free of disease and the second patient is being treated with a palliative intent. CONCLUSION: The early recognition and treatment is important as there exists a significant survival difference in patients who have synchronous primaries as opposed to those with metastatic pancreatic adenocarcinoma.
Authors: Jeannine Bachmann; Christoph W Michalski; Marc E Martignoni; Markus W Büchler; Helmut Friess Journal: HPB (Oxford) Date: 2006 Impact factor: 3.647
Authors: George J Arnaoutakis; Deepa Rangachari; Daniel A Laheru; Chris A Iacobuzio-Donahue; Ralph H Hruban; Joseph M Herman; Barish H Edil; Timothy M Pawlik; Richard D Schulick; John L Cameron; Avedis Meneshian; Stephen C Yang; Christopher L Wolfgang Journal: J Gastrointest Surg Date: 2011-07-02 Impact factor: 3.452
Authors: N Eriguchi; S Aoyagi; M Hara; K Okuda; T Tamae; S Fukuda; K Hashino; S Sato; K Fujiki; S Furukawa; A Jimi Journal: Surg Today Date: 2000 Impact factor: 2.549
Authors: Christine A Iacobuzio-Donahue; Baojin Fu; Shinichi Yachida; Mingde Luo; Hisashi Abe; Clark M Henderson; Felip Vilardell; Zheng Wang; Jesse W Keller; Priya Banerjee; Joseph M Herman; John L Cameron; Charles J Yeo; Marc K Halushka; James R Eshleman; Marian Raben; Alison P Klein; Ralph H Hruban; Manuel Hidalgo; Daniel Laheru Journal: J Clin Oncol Date: 2009-03-09 Impact factor: 44.544
Authors: David L Saltman; Tyler J Nielsen; Davide Salina; David R Hout; Frank B McMahon; Boris R Valev; Michael Huk; Pranil K Chandra; Jeremy Spille; Robert S Seitz; Brock L Schweitzer Journal: Ther Adv Med Oncol Date: 2021-04-19 Impact factor: 8.168