| Literature DB >> 30642862 |
Nabil Belfeki1, Gopinath Shankarasivam1, Damienne Declerck2, Sylvain Diamantis1.
Abstract
Autoimmune myelofibrosis is a distinct clinicopathological entity that occurs with autoimmune disorders. We report the case of a 44-year-old woman admitted with pancytopenia and clinical features of systemic lupus erythematosus, Sjogren's syndrome and antiphospholipid antibodies syndrome. Bone marrow biopsy showed decreased global cells and an increase of reticulin fibres on argentic coloration, consistent with myelofibrosis. The JAK2 V617, Myeloproliferative leukemia (MPL) and calreticulin mutations were negative. The patient's condition improved after treatment with hydroxychloroquine, vitamin K antagonists and prednisone. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.Entities:
Keywords: haematology (incl blood transfusion); immunology; systemic lupus erythematosus
Mesh:
Substances:
Year: 2019 PMID: 30642862 PMCID: PMC6340527 DOI: 10.1136/bcr-2018-227520
Source DB: PubMed Journal: BMJ Case Rep ISSN: 1757-790X