Literature DB >> 30642851

Myeloid sarcoma presenting as an unusual limbal mass.

Rachna Meel1, Arjun Desai2, Nripen Gaur2, Sameer Bakhshi3.   

Abstract

A 19-year-old woman presented to the outpatient department with occasional ocular pain and redness and a perilimbal mass, which she noticed 5 months ago in her left eye. She had no systemic complaints. Ultrasound biomicroscopy of the mass showed a hypoechoic lesion with uniform reflectivity. The patient underwent an excision biopsy and a histopathological analysis revealed features suggestive of a granulocytic sarcoma/myeloid sarcoma. Further haematopathological evaluation confirmed concurrent acute myeloid (myelomonocytic) leukaemia French American British classification M4. There was complete remission of the ocular surface lesion and leukaemia with systemic chemotherapy. At the last follow-up of 18 months post-treatment the patient is free of disease. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  haematology (incl blood transfusion); ophthalmology

Mesh:

Year:  2019        PMID: 30642851      PMCID: PMC6340522          DOI: 10.1136/bcr-2018-226284

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  17 in total

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Review 8.  Ophthalmic manifestations of acute leukaemias: the ophthalmologist's role.

Authors:  T Sharma; J Grewal; S Gupta; P I Murray
Journal:  Eye (Lond)       Date:  2004-07       Impact factor: 3.775

9.  Myeloid sarcoma is associated with superior event-free survival and overall survival compared with acute myeloid leukemia.

Authors:  Apostolia-Maria Tsimberidou; Hagop M Kantarjian; Sijin Wen; Michael J Keating; Susan O'Brien; Mark Brandt; Sherry Pierce; Emil J Freireich; L Jeffrey Medeiros; Elihu Estey
Journal:  Cancer       Date:  2008-09-15       Impact factor: 6.860

10.  Acute monocytic leukemia recurring as bilateral perilimbal infiltrates. Immunohistochemical and ultrastructural confirmation.

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Journal:  Ophthalmology       Date:  1985-12       Impact factor: 12.079

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  2 in total

1.  Relapsed acute myeloid leukemia presenting as conjunctival myeloid sarcoma: a case report.

Authors:  Joong Hyun Park; Yengwoo Son; Joon Young Hyon; Ji Yun Lee; Hyun Sun Jeon
Journal:  BMC Ophthalmol       Date:  2022-02-10       Impact factor: 2.209

Review 2.  Early Ophthalmological Manifestations of Acute Myeloid Leukemia: Current Perspectives.

Authors:  Nasrine Anais El Salloukh; Dany G Hage; Anna Z Bashshur; Wajiha Jurdi Kheir
Journal:  Clin Ophthalmol       Date:  2022-07-01
  2 in total

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