Mustafa Güdük1, Koray Özduman2, Mustafa Necmettin Pamir2. 1. Department of Neurosurgery, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey. Electronic address: mustafaguduk@gmail.com. 2. Department of Neurosurgery, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
Abstract
OBJECTIVE: Sphenoid wing meningiomas are the third most common group of intracranial meningiomas. Their management is a challenge because of their bone invasion potential and their proximity to neurovascular structures and the cavernous sinus. METHODS: A cohort of 141 patients with sphenoid wing meningioma who were operated on and followed up between 1986 and 2018 were retrospectively analyzed. Demographic data, clinical and radiologic features, surgical results, and follow-up data are presented. The effects of adjuvant treatments (radiosurgery, radiotherapy, and chemotherapy) are reviewed. The invasion pattern of tumors and other factors were noted to analyze the extent of resection. Recurrence/regrowth rates were also analyzed. RESULTS: There were 96 female and 45 male patients with a median age of 51 years (range, 17-87 years). The median follow-up was 62 months (range, 1-303 months). Tumors were grouped as spheno-orbital (31 patients), lateral (34 patients), middle (35 patients), and medial (41 patients). Gross total resection was achieved in 98 patients, and 43 tumors were resected subtotally. One hundred and twenty of these cases had World Health Organization grade I pathology, whereas the remainder had grade II. In the follow-up, there were 14 recurrences of totally resected tumors, and 24 regrowths were observed in the subtotally resected group. No invasion pattern was strongly predictive of extent of resection alone, and a scoring system was built up and proposed. CONCLUSIONS: Sphenoid wing meningioma is a large group with characteristics associated with skull base meningiomas and convexity meningiomas. The results of surgery and other adjuvant treatments are heterogeneous.
OBJECTIVE:Sphenoid wing meningiomas are the third most common group of intracranial meningiomas. Their management is a challenge because of their bone invasion potential and their proximity to neurovascular structures and the cavernous sinus. METHODS: A cohort of 141 patients with sphenoid wing meningioma who were operated on and followed up between 1986 and 2018 were retrospectively analyzed. Demographic data, clinical and radiologic features, surgical results, and follow-up data are presented. The effects of adjuvant treatments (radiosurgery, radiotherapy, and chemotherapy) are reviewed. The invasion pattern of tumors and other factors were noted to analyze the extent of resection. Recurrence/regrowth rates were also analyzed. RESULTS: There were 96 female and 45 male patients with a median age of 51 years (range, 17-87 years). The median follow-up was 62 months (range, 1-303 months). Tumors were grouped as spheno-orbital (31 patients), lateral (34 patients), middle (35 patients), and medial (41 patients). Gross total resection was achieved in 98 patients, and 43 tumors were resected subtotally. One hundred and twenty of these cases had World Health Organization grade I pathology, whereas the remainder had grade II. In the follow-up, there were 14 recurrences of totally resected tumors, and 24 regrowths were observed in the subtotally resected group. No invasion pattern was strongly predictive of extent of resection alone, and a scoring system was built up and proposed. CONCLUSIONS:Sphenoid wing meningioma is a large group with characteristics associated with skull base meningiomas and convexity meningiomas. The results of surgery and other adjuvant treatments are heterogeneous.
Authors: Waseem Masalha; Dieter Henrik Heiland; Christine Steiert; Marie T Krüger; Daniel Schnell; Pamela Heiland; Marco Bissolo; Anca-L Grosu; Oliver Schnell; Jürgen Beck; Jürgen Grauvogel Journal: Cancers (Basel) Date: 2022-04-28 Impact factor: 6.575
Authors: Alexandra Gomes Dos Santos; Wellingson Silva Paiva; Leila Maria da Roz; Marcelo Prudente do Espirito Santo; Manoel Jacobsen Teixeira; Eberval G Figueiredo; Vinicius Trindade Gomes da Silva Journal: Surg Neurol Int Date: 2022-07-22
Authors: Theresa A Elder; Hana Yokoi; A Jessey Chugh; Carlito Lagman; Osmond Wu; Christina Huang Wright; Abhishek Ray; Nicholas Bambakidis Journal: J Neurol Surg B Skull Base Date: 2019-12-23