| Literature DB >> 30638946 |
Paola Hoff Alves1, Roberta Taufer Boff2, Afonso Luis Barth3, Andreza Francisco Martins4.
Abstract
Here, we evaluated the combinations of antibiotics polymyxin B (PMB), tigecycline (TGC) and meropenem (MEM) by time-kill curves (TKC) against carbapenem-resistant Enterobacter cloacae isolates. Combination of PMB/TGC and PMB/MEM showed promising results in sub-inhibitory concentration of PMB indicating the possibility of reducing the dose of PMB used in the treatment.Entities:
Keywords: Carbapenemases; Meropenem; Polymyxin B; Synergism; Tigecycline
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Year: 2018 PMID: 30638946 DOI: 10.1016/j.diagmicrobio.2018.11.011
Source DB: PubMed Journal: Diagn Microbiol Infect Dis ISSN: 0732-8893 Impact factor: 2.803