José Manuel Carratalá1, Salvador Díaz Lobato2, Benjamin Brouzet3, Patricio Más-Serrano4, Begoña Espinosa3, Pere Llorens3. 1. Servicio de Urgencias, Unidad de Corta Estancia y Hospitalización a Domicilio, Hospital General de Alicante; Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIALFundación FISABIO), Alicante, España. Grupo Multidisciplinar Español para el Soporte Terapéutico con Terapia de Alto Flujo en Adultos (HISPAFLOW). 2. Servicio de Neumología, Hospital Universitario Ramón y Cajal, Madrid, España. Grupo Multidisciplinar Español para el Soporte Terapeútico con Terapia de Alto Flujo en Adultos (HISPAFLOW). 3. Servicio de Urgencias, Unidad de Corta Estancia y Hospitalización a Domicilio, Hospital General de Alicante; Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIALFundación FISABIO), Alicante, España. 4. Servicio de Farmacia. Hospital General de Alicante; Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIALFundación FISABIO), Alicante, España. División de Farmacia y Tecnología Farmacéutica. Universidad Miguel Hernández. Elche, Alicante, España.
Abstract
OBJECTIVES: To evaluate the efficacy and safety of high-flow nasal cannula (HFNC) oxygen therapy in patients in acute respiratory failure due to acute heart failure (AHF) refractory to conventional oxygen therapy or noninvasive ventilation. METHODS: Prospective observational study of patients with AHF and respiratory failure attended in an emergency department whose condition worsened after they were admitted to a short-stay unit, leading to use of HFNCs. Efficacy was assessed using a modified Borg dyspnea scale and oxygenation variables on discharge from the emergency department. Data were recorded after 24 hours on conventional oxygen therapy and after 60 and 120 minutes and 24 hours of HFNC therapy. Safety outcomes were the degree of patient comfort and the frequency of adverse events. RESULTS: Prospective observational study of patients with AHF and respiratory failure attended in an emergency department whose condition worsened after they were admitted to a short-stay unit, leading to use of HFNCs. Efficacy was assessed using a modified Borg dyspnea scale and oxygenation variables on discharge from the emergency department. Data were recorded after 24 hours on conventional oxygen therapy and after 60 and 120 minutes and 24 hours of HFNC therapy. Safety outcomes were the degree of patient comfort and the frequency of adverse events. CONCLUSION: HFNC oxygen therapy offers a treatment alternative for patients with acute respiratory failure due to AHF.
OBJECTIVES: To evaluate the efficacy and safety of high-flow nasal cannula (HFNC) oxygen therapy in patients in acute respiratory failure due to acute heart failure (AHF) refractory to conventional oxygen therapy or noninvasive ventilation. METHODS: Prospective observational study of patients with AHF and respiratory failure attended in an emergency department whose condition worsened after they were admitted to a short-stay unit, leading to use of HFNCs. Efficacy was assessed using a modified Borg dyspnea scale and oxygenation variables on discharge from the emergency department. Data were recorded after 24 hours on conventional oxygen therapy and after 60 and 120 minutes and 24 hours of HFNC therapy. Safety outcomes were the degree of patient comfort and the frequency of adverse events. RESULTS: Prospective observational study of patients with AHF and respiratory failure attended in an emergency department whose condition worsened after they were admitted to a short-stay unit, leading to use of HFNCs. Efficacy was assessed using a modified Borg dyspnea scale and oxygenation variables on discharge from the emergency department. Data were recorded after 24 hours on conventional oxygen therapy and after 60 and 120 minutes and 24 hours of HFNC therapy. Safety outcomes were the degree of patient comfort and the frequency of adverse events. CONCLUSION: HFNC oxygen therapy offers a treatment alternative for patients with acute respiratory failure due to AHF.
Entities:
Keywords:
Acute heart failure; Hospital emergency health services; Short-stay unit; High-flow nasal cannula; Insuficiencia cardiaca aguda; Servicio de urgencias hospitalarios; Unidad de corta estancia
Authors: Jens Spiesshoefer; Britta Bannwitz; Michael Mohr; Simon Herkenrath; Winfried Randerath; Paolo Sciarrone; Christian Thiedemann; Hartmut Schneider; Andrew T Braun; Michele Emdin; Claudio Passino; Michael Dreher; Matthias Boentert; Alberto Giannoni Journal: Sleep Breath Date: 2020-08-22 Impact factor: 2.816