Sietske J Tamminga1, Pieter Coenen2, Carmen Paalman3,4, Angela G E M de Boer1, Neil K Aaronson3, Hester S A Oldenburg5, Flora E van Leeuwen3, Allard J van der Beek2, Saskia F A Duijts2,3,6, Michael Schaapveld7,8. 1. Amsterdam UMC, Coronel Institute of Occupational Health, Amsterdam Public Health Research Institute, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands. 2. Department of Public and Occupational Health, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands. 3. Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands. 4. Netherlands Comprehensive Cancer Organisation (IKNL), Utrecht, The Netherlands. 5. Department of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands. 6. Department of General Practice, University of Groningen, University Medical Center Groningen, Antonius Deusinglaan 1, FA 21, 9713 AV, Groningen, The Netherlands. 7. Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands. m.schaapveld@nki.nl. 8. Netherlands Comprehensive Cancer Organisation (IKNL), Utrecht, The Netherlands. m.schaapveld@nki.nl.
Abstract
PURPOSE: To identify which factors are associated with adverse work outcome 5-10 years after diagnosis. METHODS: In this cross-sectional study, breast cancer survivors, treated between 2003 and 2008, completed a questionnaire 5-10 years after diagnosis. Adverse work outcome was defined as not having paid employment or working > 20% less compared to prediagnosis. Logistic regression analyses were conducted. RESULTS: Of 906 participants, 326 (36%) had an adverse work outcome. In multivariable analyses, the probability of an adverse work outcome increased with age (OR, 1.03; 95% CI, 1.00-1.07), time since diagnosis (OR, 1.19; 95% CI, 1.03-1.37), and was higher among women who stated that work had become less important (OR, 2.99; 95% CI, 1.94-4.62). Factors associated with a lower probability of an adverse work outcome were having sufficient financial resources (OR, 0.23; 95% CI, 0.08-0.66), higher total work ability (OR, 0.61; 95% CI, 0.54-0.69), feeling supported at work (OR, 0.52; 95% CI, 0.33-0.80), and, prior to diagnosis, having more children to take care of (OR, 0.65; 95% CI, 0.54-0.79), being able to adjust working hours (OR, 0.55; 95% CI, 0.36-0.83) and not desiring to work less hours if that were to be financially feasible (OR, 1.8; 95% CI, 1.0-3.2). CONCLUSIONS: Predominantly, work-related factors are associated with adverse work outcomes 5-10 years after diagnosis, whereas clinical factors are not. Our results need validation in prospective cohort studies, after which supportive interventions could be developed. IMPLICATIONS FOR CANCER SURVIVORS: Work-related factors should be considered in future interventions to prevent adverse work outcome 5-10 years after diagnosis.
PURPOSE: To identify which factors are associated with adverse work outcome 5-10 years after diagnosis. METHODS: In this cross-sectional study, breast cancer survivors, treated between 2003 and 2008, completed a questionnaire 5-10 years after diagnosis. Adverse work outcome was defined as not having paid employment or working > 20% less compared to prediagnosis. Logistic regression analyses were conducted. RESULTS: Of 906 participants, 326 (36%) had an adverse work outcome. In multivariable analyses, the probability of an adverse work outcome increased with age (OR, 1.03; 95% CI, 1.00-1.07), time since diagnosis (OR, 1.19; 95% CI, 1.03-1.37), and was higher among women who stated that work had become less important (OR, 2.99; 95% CI, 1.94-4.62). Factors associated with a lower probability of an adverse work outcome were having sufficient financial resources (OR, 0.23; 95% CI, 0.08-0.66), higher total work ability (OR, 0.61; 95% CI, 0.54-0.69), feeling supported at work (OR, 0.52; 95% CI, 0.33-0.80), and, prior to diagnosis, having more children to take care of (OR, 0.65; 95% CI, 0.54-0.79), being able to adjust working hours (OR, 0.55; 95% CI, 0.36-0.83) and not desiring to work less hours if that were to be financially feasible (OR, 1.8; 95% CI, 1.0-3.2). CONCLUSIONS: Predominantly, work-related factors are associated with adverse work outcomes 5-10 years after diagnosis, whereas clinical factors are not. Our results need validation in prospective cohort studies, after which supportive interventions could be developed. IMPLICATIONS FOR CANCER SURVIVORS: Work-related factors should be considered in future interventions to prevent adverse work outcome 5-10 years after diagnosis.
Entities:
Keywords:
Breast cancer; Cancer survivorship; Employment; Work
Authors: M A Greidanus; A E de Rijk; A G E M de Boer; M E M M Bos; P W Plaisier; R M Smeenk; M H W Frings-Dresen; S J Tamminga Journal: BMC Public Health Date: 2021-07-21 Impact factor: 3.295