Juan P Rodrigo1, Fabian García-Velasco1, Petra Ambrosch2, Vincent Vander Poorten3,4, Carlos Suárez1, Andrés Coca-Pelaz1, Primoz Strojan5, Kate Hutcheson6, Benedikt J Folz7, Manuel Bernal-Sprekelsen8, Alessandra Rinaldo9, Carl E Silver10, Alfio Ferlito11. 1. Department of Otolaryngology, Hospital Universitario Central de Asturias, University of Oviedo, ISPA, IUOPA, CIBERONC, Oviedo, Spain. 2. Department of Otorhinolaryngology, Head and Neck Surgery, Christian-Albrechts-University of Kiel, Kiel, Germany. 3. Otorhinolaryngology, Head and Neck Surgery, University Hospitals Leuven, Leuven, Belgium. 4. Department of Oncology, Section Head and Neck Oncology, KU Leuven, Leuven, Belgium. 5. Department of Radiation Oncology, Institute of Oncology, Ljubljana, Slovenia. 6. Department of Head and Neck Surgery, Section of Speech Pathology and Audiology, MD Anderson Cancer Center, Houston, Texas. 7. ENT Department, Karl Hansen Clinic, Bad Lippspringe, Germany. 8. Department of Otolaryngology, University of Valencia, Valencia, Spain. 9. Otorhinolaryngology-Head and neck surgery, University of Udine School of Medicine, Udine, Italy. 10. Department of Surgery, University of Arizona College of Medicine, Phoenix, Arizona. 11. International Head and Neck Scientific Group, Padua, Italy.
Abstract
BACKGROUND: Data about the results of transoral laser microsurgery (TLM) in elderly patients are limited. METHODS: A retrospective study of 72 consecutive cases of glottic carcinoma (63 pT1 and 9 pT2 cases) in elderly patients (≥70 years old, mean 76 years) treated with TLM was made. A systematic review of the literature was performed. RESULTS: Six patients (8%) had postoperative complications, but no treatment-related deaths were observed. Local recurrences occurred in 12 patients (16.5%): nine with pT1 (14%) and three with pT2 (33%) tumors. Five-year disease-specific survival (DSS), overall survival, and laryngectomy-free survival were 95%, 68%, and 88%, respectively. The literature review indicated that TLM is safe and effective treatment for these patients, with few complications and good local control (>85%) and DSS (>90%) rates. CONCLUSIONS: Our results and the information from the literature show that TLM for glottic cancer in elderly patients can lead to satisfactory treatment results.
BACKGROUND: Data about the results of transoral laser microsurgery (TLM) in elderly patients are limited. METHODS: A retrospective study of 72 consecutive cases of glottic carcinoma (63 pT1 and 9 pT2 cases) in elderly patients (≥70 years old, mean 76 years) treated with TLM was made. A systematic review of the literature was performed. RESULTS: Six patients (8%) had postoperative complications, but no treatment-related deaths were observed. Local recurrences occurred in 12 patients (16.5%): nine with pT1 (14%) and three with pT2 (33%) tumors. Five-year disease-specific survival (DSS), overall survival, and laryngectomy-free survival were 95%, 68%, and 88%, respectively. The literature review indicated that TLM is safe and effective treatment for these patients, with few complications and good local control (>85%) and DSS (>90%) rates. CONCLUSIONS: Our results and the information from the literature show that TLM for glottic cancer in elderly patients can lead to satisfactory treatment results.
Authors: Changseok Lee; David Forner; Christopher W Noel; Victoria Taylor; Colin MacKay; Matthew H Rigby; Martin Corsten; Jonathan R Trites; S Mark Taylor Journal: OTO Open Date: 2021-09-29
Authors: Alberto Paderno; Davide Lancini; Paolo Bosio; Francesca Del Bon; Milena Fior; Giulia Berretti; Marco Alparone; Alberto Deganello; Giorgio Peretti; Cesare Piazza Journal: Laryngoscope Date: 2021-07-07 Impact factor: 2.970