Literature DB >> 30632871

Diagnostic spectrum and time intervals in Sweden's first diagnostic center for patients with nonspecific symptoms of cancer.

Emelie Stenman1, Karolina Palmér1, Stefan Rydén2, Charlotta Sävblom3, Inga Svensson4, Carsten Rose5, Jianguang Ji1, Mef Nilbert6,7,8, Jan Sundquist1.   

Abstract

BACKGROUND: Fast-track referral is an increasingly used method for diagnostic evaluation of patients suspected of having cancer. This approach is challenging and not used as often for patients with only nonspecific symptoms. In order to expedite the diagnostics for these patients, we established Sweden's first Diagnostic Center (DC) focusing on outcomes related to diagnoses and diagnostic time intervals.
MATERIAL AND METHODS: The study was designed as a prospective cohort study. Patients aged ≥18 years who presented in primary care with nonspecific symptoms of a serious disease were eligible for referral to the DC after having completed an initial investigation. Acceptable diagnostic time intervals were defined to be a maximum of 15 days in primary care and 22 days at the DC. Diagnostic outcome, length of diagnostic time intervals and patient satisfaction were evaluated.
RESULTS: A total of 290 patients were included in the study. Cancer was diagnosed in 22.1%, other diseases in 64.1%, and no diagnosis was identified in 13.8% of these patients. Patients diagnosed with cancer were older, had shorter patient interval (time from first symptom to help-seeking), shorter DC-interval (time from referral decision in primary care to diagnosis) and showed a greater number of symptoms compared to patients with no diagnosis. The median primary care interval was 21 days and the median DC interval was 11 days. Few symptoms, no diagnosis, female sex, longer patient interval, and incomplete investigations were associated with prolonged diagnostic time intervals. Patient satisfaction was high; 86% of patients reported a positive degree of satisfaction with the diagnostic procedures.
CONCLUSIONS: We demonstrated that the DC concept is feasible with a diagnosis reached in 86.2% of the patients in addition to favorable diagnostic time intervals at the DC and a high degree of patient satisfaction.

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Year:  2019        PMID: 30632871     DOI: 10.1080/0284186X.2018.1537506

Source DB:  PubMed          Journal:  Acta Oncol        ISSN: 0284-186X            Impact factor:   4.089


  8 in total

1.  The pathway and characteristics of patients with non-specific symptoms of cancer: a systematic review.

Authors:  Ellen Jensen; Jette Kolding Kristensen; Rikke Tveden Bjerglund; Søren Paaske Johnsen; Janus Laust Thomsen
Journal:  BMC Cancer       Date:  2022-05-23       Impact factor: 4.638

2.  Diagnostic center for primary care patients with nonspecific symptoms and suspected cancer: compliance to workflow and accuracy of tests and examinations.

Authors:  Emelie Stenman; Karolina Palmér; Stefan Rydén; Charlotta Sävblom; Jianguang Ji; Jan Sundquist
Journal:  Scand J Prim Health Care       Date:  2021-05-06       Impact factor: 2.581

3.  Cross-sectional study using primary care and cancer registration data to investigate patients with cancer presenting with non-specific symptoms.

Authors:  Clare Pearson; Veronique Poirier; Karen Fitzgerald; Greg Rubin; Willie Hamilton
Journal:  BMJ Open       Date:  2020-01-10       Impact factor: 2.692

4.  Time Intervals Under the Lens at Sweden's First Diagnostic Center for Primary Care Patients With Nonspecific Symptoms of Cancer. A Comparison With Matched Control Patients.

Authors:  Jan Sundquist; Karolina Palmér; Stefan Rydén; Charlotta Sävblom; Jianguang Ji; Emelie Stenman
Journal:  Front Oncol       Date:  2020-11-30       Impact factor: 6.244

Review 5.  Interventions to improve early cancer diagnosis of symptomatic individuals: a scoping review.

Authors:  George N Okoli; Otto L T Lam; Viraj K Reddy; Leslie Copstein; Nicole Askin; Anubha Prashad; Jennifer Stiff; Satya Rashi Khare; Robyn Leonard; Wasifa Zarin; Andrea C Tricco; Ahmed M Abou-Setta
Journal:  BMJ Open       Date:  2021-11-09       Impact factor: 2.692

6.  Delays in Cancer Diagnostic Testing at a Quick Referral Unit in Spain during COVID-19.

Authors:  Xavier Bosch; Manuel Torres; Pedro Moreno; Alfonso López-Soto
Journal:  Diagnostics (Basel)       Date:  2021-11-12

7.  Diagnostic potential of circulating cell-free nuclear and mitochondrial DNA for several cancer types and nonmalignant diseases: A study on suspected cancer patients.

Authors:  Kristina Sundquist; Jan Sundquist; Anna Hedelius; Ashfaque A Memon
Journal:  Mol Carcinog       Date:  2020-10-13       Impact factor: 4.784

8.  Use and diagnostic outcomes of cancer patient pathways in Denmark - is the place of initial diagnostic work-up an important factor?

Authors:  Susanne Oksbjerg Dalton; John Brodersen; Christina Sadolin Damhus; Volkert Siersma; Anna Rubach Birkmose
Journal:  BMC Health Serv Res       Date:  2022-01-31       Impact factor: 2.655

  8 in total

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