Yi-Hao Peng1,2,3, Chien-Wen Huang4,5,6, Che-Yi Chou7,8, Hung-Jie Chiou9, Hsuan-Ju Chen10,11, Trong-Neng Wu12, Wen-Chao Ho1. 1. Department of Public Health, China Medical University, Taichung, Taiwan, ROC. 2. Department of Respiratory Therapy, Asia University Hospital, Asia University, Taichung, Taiwan, ROC. 3. Department of Respiratory Therapy, China Medical University, Taichung, Taiwan, ROC. 4. Department of Internal Medicine, Division of Chest Medicine, Asia University Hospital, Taichung, Taiwan, ROC. 5. Department of Biotechnology, College of Medical and Health Science, Asia University, Taichung, Taiwan, ROC. 6. Institute of Molecular Biology, College of Life Sciences, National Chung Hsing University, Taichung, Taiwan, ROC. 7. Department of Internal Medicine, Division of Nephrology, Asia University Hospital, Taichung, Taiwan, ROC. 8. Department of Post-baccalaureate Veterinary Medicine, Asia University, Taichung, Taiwan, ROC. 9. Department of Surgery, Division of Urology, Asia University Hospital, Taichung, Taiwan, ROC. 10. College of Medicine, China Medical University, Taichung, Taiwan, ROC. 11. Management Office for Health Data, China Medical University Hospital, Taichung, Taiwan, ROC. 12. Department of Health Care Administration, Asia University, Taichung, Taiwan, ROC.
Abstract
OBJECTIVE: The association between asthma and benign prostatic hyperplasia (BPH) has rarely been explored. We investigated whether male asthmatic patients had an increased risk of BPH by conducting this retrospective nationwide population-based study. METHODS: We utilized data derived from the National Health Insurance Research Database (NHIRD) in Taiwan. A total of 9778 male patients aged >40 years who were newly diagnosed with asthma between 2000 and 2006 were included in the asthma group. Male enrollees without asthma were selected as the non-asthma group from the same database. Both the groups were followed up until the end of 2013. We performed Cox proportional hazard regression analysis to estimate the risk of BPH and transurethral resection of the prostate (TURP) in the male patients with asthma compared with that in those without asthma. RESULTS: The risk of BPH and TURP in the asthma group was 1.40-fold (95% confidence interval [CI] = 1.30-1.42) and 1.30-fold (95% CI= 1.31-1.50) higher than that in the non-asthma group, respectively, after adjusting for comorbidities, relevant medications and number of annual outpatient visits. CONCLUSIONS: The male patients with asthma were found to have a higher risk of BPH than did those without asthma.
OBJECTIVE: The association between asthma and benign prostatic hyperplasia (BPH) has rarely been explored. We investigated whether male asthmatic patients had an increased risk of BPH by conducting this retrospective nationwide population-based study. METHODS: We utilized data derived from the National Health Insurance Research Database (NHIRD) in Taiwan. A total of 9778 male patients aged >40 years who were newly diagnosed with asthma between 2000 and 2006 were included in the asthma group. Male enrollees without asthma were selected as the non-asthma group from the same database. Both the groups were followed up until the end of 2013. We performed Cox proportional hazard regression analysis to estimate the risk of BPH and transurethral resection of the prostate (TURP) in the male patients with asthma compared with that in those without asthma. RESULTS: The risk of BPH and TURP in the asthma group was 1.40-fold (95% confidence interval [CI] = 1.30-1.42) and 1.30-fold (95% CI= 1.31-1.50) higher than that in the non-asthma group, respectively, after adjusting for comorbidities, relevant medications and number of annual outpatient visits. CONCLUSIONS: The male patients with asthma were found to have a higher risk of BPH than did those without asthma.
Entities:
Keywords:
Asthma; benign prostatic hyperplasia; cohort study; epidemiology; transurethral resection of the prostate