| Literature DB >> 30632580 |
R Mukherjee1, M van de Kaa, J Garssen, R J Pieters, A D Kraneveld, L E M Willemsen.
Abstract
Lactulose, a non-digestible oligosaccharide and functional food, promotes Bifidobacteria growth. Here we show that lactulose, beyond its prebiotic action, may have direct immunomodulatory effects as well. In synergy with CpG-ODN, a bacterial DNA mimetic, lactulose enhances basolateral concentrations of IFN-γ, IL-10, and galectin-9 in the co-culture model of epithelial and immune cells.Entities:
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Year: 2019 PMID： 30632580 DOI： 10.1039/c8fo02376j
Source DB: PubMed Journal: Food Funct ISSN： 2042-6496 Impact factor: 5.396