| Literature DB >> 30632287 |
Raquel Nunes da Silva1,2, Catarina C Costa1, Maria J G Santos1, Mariana Q Alves2, Susana S Braga1, Sandra I Vieira2, João Rocha3, Artur M S Silva1, Samuel Guieu1,3.
Abstract
A fluorescent dye was decorated with water-soluble pyridinium groups in order to be applied in the detection of cyclodextrins or DNA. The dye displays an enhancement of its emission intensity when the internal rotations are restricted due to the formation of an inclusion complex with cyclodextrins or upon interaction with DNA. In vivo, the fluorescent probe can stain protein aggregates with a selectivity comparable to the widely used Proteostat®.Entities:
Keywords: DNA; aggregation-induced emission enhancement; cyclodextrins; fluorescent probes; protein aggregates
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Year: 2019 PMID： 30632287 DOI： 10.1002/asia.201801606
Source DB: PubMed Journal: Chem Asian J ISSN： 1861-471X