Bo Yang1, Zhong-Xia Wang1,2. 1. CAS Key Laboratory of Soft Matter Chemistry and Department of Chemistry , University of Science and Technology of China , Hefei , Anhui 230026 , P. R. China. 2. Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin 300072 , P. R. China.
Abstract
A methodology that allows for the construction of C-P bonds via the nickel-catalyzed cross-coupling of organoammonium salts with appropriate phosphorus nucleophiles has been developed. Aryl-, pyridyl-, benzyl-, and allyl-ammonium triflates can be employed as the electrophiles. The employed phosphorus-based nucleophiles included diaryl/dibutyl phosphine oxide, dialkyl phosphonates, and ethyl phenylphosphinate. Functional groups OMe, CN, CF3, F, Cl, C(O)NMe2, and C(O) tBu were tolerated.
A methodology that allows for the construction of C-P bonds via the nickel-catalyzed cross-coupling of pan class="Chemical">organoammonium salts with appropriate phosphorus nucleophiles has been developed. Aryl-, pyridyl-, benzyl-, and allyl-ammonium triflates can be employed as the electrophiles. The employed phosphorus-based nucleophiles included diaryl/dibutyl phosphine oxide, dialkyl phosphonates, and ethyl phenylphosphinate. Functional groups OMe, CN, CF3, F, Cl, C(O)NMe2, and C(O) tBu were tolerated.