Literature DB >> 30626724

Potential Effects of Aspirin on Lysosomal Biogenesis and Amyloid-β Clearance: An Old Drug and Novel Insights in Alzheimer's Disease Therapy.

Helen M Melo1.   

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Year:  2019        PMID： 30626724      PMCID： PMC6360281          DOI： 10.1523/JNEUROSCI.2283-18.2018

Source DB:  PubMed          Journal:  J Neurosci        ISSN： 0270-6474            Impact factor:   6.167


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  14 in total

1.  PPARα in lysosomal biogenesis: A perspective.

Authors:  Arunava Ghosh; Kalipada Pahan
Journal:  Pharmacol Res       Date:  2015-11-24       Impact factor: 7.658

2.  Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer's disease amyloid plaques.

Authors:  Swetha Gowrishankar; Peng Yuan; Yumei Wu; Matthew Schrag; Summer Paradise; Jaime Grutzendler; Pietro De Camilli; Shawn M Ferguson
Journal:  Proc Natl Acad Sci U S A       Date:  2015-06-29       Impact factor: 11.205

3.  Activation of peroxisome proliferator-activated receptor α induces lysosomal biogenesis in brain cells: implications for lysosomal storage disorders.

Authors:  Arunava Ghosh; Malabendu Jana; Khushbu Modi; Frank J Gonzalez; Katherine B Sims; Elizabeth Berry-Kravis; Kalipada Pahan
Journal:  J Biol Chem       Date:  2015-03-06       Impact factor: 5.157

4.  Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP.

Authors:  Grant T Corbett; Frank J Gonzalez; Kalipada Pahan
Journal:  Proc Natl Acad Sci U S A       Date:  2015-06-15       Impact factor: 11.205

5.  Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for beta-amyloid peptide over-production and localization in Alzheimer's disease.

Authors:  W H Yu; A Kumar; C Peterhoff; L Shapiro Kulnane; Y Uchiyama; B T Lamb; A M Cuervo; R A Nixon
Journal:  Int J Biochem Cell Biol       Date:  2004-12       Impact factor: 5.085

6.  Lysosomal enzyme tripeptidyl peptidase 1 destabilizes fibrillar Aβ by multiple endoproteolytic cleavages within the β-sheet domain.

Authors:  Santiago Solé-Domènech; Ana V Rojas; Gia G Maisuradze; Harold A Scheraga; Peter Lobel; Frederick R Maxfield
Journal:  Proc Natl Acad Sci U S A       Date:  2018-01-29       Impact factor: 11.205

7.  Enhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesis.

Authors:  Qingli Xiao; Ping Yan; Xiucui Ma; Haiyan Liu; Ronaldo Perez; Alec Zhu; Ernesto Gonzales; Jack M Burchett; Dorothy R Schuler; John R Cirrito; Abhinav Diwan; Jin-Moo Lee
Journal:  J Neurosci       Date:  2014-07-16       Impact factor: 6.167

Review 8.  Alzheimer's disease.

Authors:  Colin L Masters; Randall Bateman; Kaj Blennow; Christopher C Rowe; Reisa A Sperling; Jeffrey L Cummings
Journal:  Nat Rev Dis Primers       Date:  2015-10-15       Impact factor: 52.329

Review 9.  Regulation mechanisms and signaling pathways of autophagy.

Authors:  Congcong He; Daniel J Klionsky
Journal:  Annu Rev Genet       Date:  2009       Impact factor: 16.830

10.  Aspirin Induces Lysosomal Biogenesis and Attenuates Amyloid Plaque Pathology in a Mouse Model of Alzheimer's Disease via PPARα.

Authors:  Sujyoti Chandra; Malabendu Jana; Kalipada Pahan
Journal:  J Neurosci       Date:  2018-07-02       Impact factor: 6.167
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