Leonardo de Souza Vasconcellos1, Andy Petroianu2, Juliana Ribeiro Romeiro3, Wilson Campos Tavares Junior4, Vivian Resende5. 1. PhD, Associate Professor, Complementary Propaedeutics Department, School of Medicine, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte-MG, Brazil. Scientific, intellectual, conception and design of the study; acquisition, analysis and interpretation of data; technical procedures; statistical analysis; manuscript preparation and writing. 2. PhD, Full Professor, Department of Surgery, Faculty of Medicine, UFMG, Researcher 1B CNPq, Belo Horizonte-MG, Brazil.Scientific, intellectual, conception and design of the study; acquisition, analysis and interpretation of data; technical procedures; manuscript preparation and writing; critical revision; final approval. 3. PhD, School of Medicine, UFMG, Belo Horizonte-MG, Brazil. Acquisition of data, technical procedures. 4. MD, MSc, Clinical Hospital, UFMG, Belo Horizonte-MG, Brazil. Acquisition of data, technical procedures. 5. PhD, Associate Professor, Department of Surgery, School of Medicine, UFMG, Belo Horizonte-MG, Brazil. Scientific, intellectual, conception and design of the study; acquisition, analysis and interpretation of data; technical procedures; statistical analysis; manuscript preparation and writing; critical revision.
Abstract
PURPOSE: To evaluate a possible relationship between the size of the spleen and values of circulating blood elements in patients with schistosomatic splenomegaly. METHODS: ixty one patients with hepatosplenic schistosomiasis mansoni underwent a clinical exam and peripheral venous blood was collected for a hemogram. The erythrocyte, hemoglobin, hematocrit, leukocyte, and platelet values were determined. All patients underwent abdominal ultrasound to measure the spleen. The hematological test results were compared to the size of the spleen. RESULTS: The size of the spleen varied from 14.0 to 28.4 (19.9 ± 3.7) cm according to the ultrasound image. Thrombocytopenia was observed 58 (95%) patients, leukopenia in 55 (90%) patients, and anemia in 32 (52.4%) patients. Leukopenia was proportional to splenomegaly. CONCLUSION: Schistosomal splenomegaly leads to leukopenia in direct proportion to the size of the spleen.
PURPOSE: To evaluate a possible relationship between the size of the spleen and values of circulating blood elements in patients with schistosomatic splenomegaly. METHODS: ixty one patients with hepatosplenic schistosomiasis mansoni underwent a clinical exam and peripheral venous blood was collected for a hemogram. The erythrocyte, hemoglobin, hematocrit, leukocyte, and platelet values were determined. All patients underwent abdominal ultrasound to measure the spleen. The hematological test results were compared to the size of the spleen. RESULTS: The size of the spleen varied from 14.0 to 28.4 (19.9 ± 3.7) cm according to the ultrasound image. Thrombocytopenia was observed 58 (95%) patients, leukopenia in 55 (90%) patients, and anemia in 32 (52.4%) patients. Leukopenia was proportional to splenomegaly. CONCLUSION: Schistosomal splenomegaly leads to leukopenia in direct proportion to the size of the spleen.