Literature DB >> 30623687

Anti-DFS70 antibodies: an update on our current understanding and their clinical usefulness.

Michael Mahler1, Luis E Andrade2,3, Carlos A Casiano4, Kishore Malyavantham1, Marvin J Fritzler5.   

Abstract

INTRODUCTION: Anti-DFS70 antibodies and their clinical associations remain an immunological paradox. Unlike other antinuclear antibodies (ANA), there is a growing body of evidence that anti-DFS70 antibodies, when present in high titers and in isolation (without accompanying other antibodies), are useful to aid in the exclusion of ANA associated rheumatic diseases. Areas covered: This review aims to analyze and interpret the current published knowledge and recent findings to provide guidance in the use of anti-DFS70 antibodies to analyze associations of this unique autoantibody. Expert commentary: Although the association of anti-DFS70 antibodies is still unknown, their use as a biomarker that can aid in the exclusion of ANA related diseases is well-established.

Entities:  

Keywords:  ANA; ANA associated rheumatic disease; Autoantibodies; anti-DFS70; antinuclear antibodies; dense fine speckled; indirect immunofluorescence

Mesh：

Substances：

Year:  2019        PMID： 30623687     DOI： 10.1080/1744666X.2019.1562903

Source DB:  PubMed          Journal:  Expert Rev Clin Immunol        ISSN： 1744-666X            Impact factor:   4.473


  18 in total

1.  Negative specificity for DSF70 in ANA positive leprosy sera.

Authors:  Sandra Lúcia Euzébio Ribeiro; Gabriel Pacifico Seabra Nunes; Henrique Euzébio Guedes de Freitas; Cristóvão Mangueira; Morton Aaron Scheinberg
Journal:  Clin Rheumatol       Date:  2019-07-05       Impact factor: 2.980

2.  How to report the antinuclear antibodies (anti-cell antibodies) test on HEp-2 cells: guidelines from the ICAP initiative.

Authors:  Carlos Alberto von Mühlen; Ignacio Garcia-De La Torre; Maria Infantino; Jan Damoiseaux; Luis E C Andrade; Orlando Gabriel Carballo; Karsten Conrad; Paulo Luiz Carvalho Francescantonio; Marvin J Fritzler; Manfred Herold; Werner Klotz; Wilson de Melo Cruvinel; Tsuneyo Mimori; Minoru Satoh; Lucile Musset; Edward K L Chan
Journal:  Immunol Res       Date:  2021-10-09       Impact factor: 2.829

3.  The temporal course of T- and B-cell responses to vaccination with BNT162b2 and mRNA-1273.

Authors:  Robert Markewitz; Daniela Pauli; Justina Dargvainiene; Katja Steinhagen; Sarah Engel; Victor Herbst; Dorinja Zapf; Christina Krüger; Shahpour Sharifzadeh; Benjamin Schomburg; Frank Leypoldt; Jan Rupp; Siegfried Görg; Ralf Junker; Klaus-Peter Wandinger
Journal:  Clin Microbiol Infect       Date:  2021-09-20       Impact factor: 13.310

4.  Prevalence of anti-DFS70 autoantibodies in a Latin American cohort of patients with systemic lupus erythematosus and without autoimmune diseases.

Authors:  Cristian C Aragón; Iván Posso-Osorio; Germán Puerta; Juan-David González; Juan-Camilo Naranjo; Alex Echeverri; Eliana Ortíz; Ivana Nieto-Aristizábal; María Claudia Barrera; Lady J Ríos-Serna; Gabriel J Tobón
Journal:  Clin Rheumatol       Date:  2020-02-22       Impact factor: 2.980

5.  Pattern of antinuclear antibody and antiextractable nuclear antigen antibody test requisitions in Riyadh.

Authors:  Najla Ali Alghabban; Zahid Shakoor
Journal:  J Family Med Prim Care       Date:  2019-11-15

6.  Anti-DFS70 Antibodies Among Patient and Healthy Population Cohorts in China: Results From a Multicenter Training Program Showing Spontaneous Abortion and Pediatric Systemic Autoimmune Rheumatic Diseases Are Common in Anti-DFS70 Positive Patients.

Authors:  Bing Zheng; Zhiqing Wang; Rodrigo A Mora; Aiping Liu; Chihui Li; Dengtao Liu; Fuying Zhai; Huiyuan Liu; Huiyun Gong; Jiaye Zhou; Jing Liu; Li Chen; Lijun Wu; Lin Yuan; Lina Ying; Loujian Jie; Meifang He; Meng Hao; Ping Xu; Qiuwei Lu; Shanshan Han; Shishi Chen; Shuimian Chen; Shunfei Zhu; Weihua Sun; Xiaoying Guo; Yajuan Chen; Yan Wang; Yemin Qu; Zhen Li; Zhenzhen Niu; Zhongyan Han; Edward K L Chan
Journal:  Front Immunol       Date:  2020-10-02       Impact factor: 7.561

7.  Prevalence of anti-dense fine speckled 70 antibodies in healthy individuals and patients with antinuclear antibody-associated autoimmune rheumatic diseases in Japan.

Authors:  Nobuhide Hayashi; Kenichi Uto; Akiko Imanishi; Daisuke Sugiyama; Akio Morinobu; Jun Saegusa
Journal:  Medicine (Baltimore)       Date:  2021-03-05       Impact factor: 1.817

Review 8.  Twenty years of research on the DFS70/LEDGF autoantibody-autoantigen system: many lessons learned but still many questions.

Authors:  Greisha L Ortiz-Hernandez; Evelyn S Sanchez-Hernandez; Carlos A Casiano
Journal:  Auto Immun Highlights       Date:  2020-02-03

9.  Diagnosing Organic Causes of Schizophrenia Spectrum Disorders: Findings from a One-Year Cohort of the Freiburg Diagnostic Protocol in Psychosis (FDPP).

Authors:  Dominique Endres; Miriam Matysik; Bernd Feige; Nils Venhoff; Tina Schweizer; Maike Michel; Sophie Meixensberger; Kimon Runge; Simon J Maier; Kathrin Nickel; Karl Bechter; Horst Urbach; Katharina Domschke; Ludger Tebartz van Elst
Journal:  Diagnostics (Basel)       Date:  2020-09-14

10.  Dense fine speckled immunofluorescence pattern in a Chinese population: Prevalence and clinical association.

Authors:  Keyi Zhang; Zhenzhen Su; Jing Hu; Zhuochun Huang; Chaojun Hu; Bin Yang
Journal:  J Clin Lab Anal       Date:  2021-12-24       Impact factor: 2.352
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