Literature DB >> 30623465

On the interpretation of the hazard ratio in Cox regression.

Jan De Neve1, Thomas A Gerds2.   

Abstract

We argue that the term "relative risk" should not be used as a synonym for "hazard ratio" and encourage to use the probabilistic index as an alternative effect measure for Cox regression. The probabilistic index is the probability that the event time of an exposed or treated subject exceeds the event time of an unexposed or untreated subject conditional on the other covariates. It arises as a well known and simple transformation of the hazard ratio and nicely reveals the interpretational limitations. We demonstrate how the probabilistic index can be obtained using the R-package Publish.
© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  Cox regression model; hazard ratio; probabilistic index; relative risk; survival analysis

Mesh:

Year:  2019        PMID: 30623465     DOI: 10.1002/bimj.201800255

Source DB:  PubMed          Journal:  Biom J        ISSN: 0323-3847            Impact factor:   2.207


  4 in total

1.  Associations of interpersonal trust with juvenile offending/conduct disorder, callous-unemotional traits, and criminal recidivism.

Authors:  Marcel Aebi; Melanie Haynes; Cornelia Bessler; Gregor Hasler
Journal:  Sci Rep       Date:  2022-05-09       Impact factor: 4.996

2.  Associations of Daily Steps and Step Intensity With Incident Diabetes in a Prospective Cohort Study of Older Women: The OPACH Study.

Authors:  Alexis C Garduno; Andrea Z LaCroix; Michael J LaMonte; David W Dunstan; Kelly R Evenson; Guangxing Wang; Chongzhi Di; Benjamin T Schumacher; John Bellettiere
Journal:  Diabetes Care       Date:  2022-02-01       Impact factor: 17.152

3.  Delayed treatment effects, treatment switching and heterogeneous patient populations: How to design and analyze RCTs in oncology.

Authors:  Robin Ristl; Nicolás M Ballarini; Heiko Götte; Armin Schüler; Martin Posch; Franz König
Journal:  Pharm Stat       Date:  2020-08-23       Impact factor: 1.894

4.  Survival outcomes for patients with four treatments in stages I-III esophageal squamous cell carcinoma: a SEER analysis.

Authors:  Jingyang Wu; Jiansheng Yang; Xianbin Lin; Liang'an Lin; Wentan Jiang; Chengke Xie
Journal:  Transl Cancer Res       Date:  2021-05       Impact factor: 1.241

  4 in total

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