Literature DB >> 30623292

Stem cell replication, somatic mutations and role of randomness in the development of cancer.

Vittorio Perduca1,2, Ludmil B Alexandrov3, Michelle Kelly-Irving4,5, Cyrille Delpierre4,5, Hanane Omichessan2, Mark P Little6, Paolo Vineis7, Gianluca Severi8,9.   

Abstract

An intense scientific debate has recently taken place relating to the "bad luck" hypothesis in cancer development, namely that intrinsic random, and therefore unavoidable, mutagenic events would have a predominant role in tumorigenesis. In this article we review the main contributions to this debate and explain the reasons why the claim that cancer is mostly explained by intrinsic random factors is unsupported by data and theoretical models. In support of this, we present an analysis showing that smoking-induced mutations are more predictive of cancer risk than the lifetime number of stem cell cellular divisions.

Entities:  

Keywords:  Cancer; Environment; Epidemiology; Risk factors; Somatic mutations

Mesh：

Year:  2019        PMID： 30623292     DOI： 10.1007/s10654-018-0477-6

Source DB:  PubMed          Journal:  Eur J Epidemiol        ISSN： 0393-2990            Impact factor:   8.082


  30 in total

1.  Judgment under Uncertainty: Heuristics and Biases.

Authors:  A Tversky; D Kahneman
Journal:  Science       Date:  1974-09-27       Impact factor: 47.728

2.  Cancer risk: role of chance overstated.

Authors:  Christopher Wild; Paul Brennan; Martyn Plummer; Freddie Bray; Kurt Straif; Jiri Zavadil
Journal:  Science       Date:  2015-02-05       Impact factor: 47.728

3.  Cancer etiology. Variation in cancer risk among tissues can be explained by the number of stem cell divisions.

Authors:  Cristian Tomasetti; Bert Vogelstein
Journal:  Science       Date:  2015-01-02       Impact factor: 47.728

Review 4.  Role of mutagenicity in asbestos fiber-induced carcinogenicity and other diseases.

Authors:  Sarah X L Huang; Marie-Claude Jaurand; David W Kamp; John Whysner; Tom K Hei
Journal:  J Toxicol Environ Health B Crit Rev       Date:  2011       Impact factor: 6.393

Review 5.  Cancer immunoediting from immune surveillance to immune escape.

Authors:  Ryungsa Kim; Manabu Emi; Kazuaki Tanabe
Journal:  Immunology       Date:  2007-03-26       Impact factor: 7.397

Review 6.  How tumours escape mass destruction.

Authors:  T J Stewart; S I Abrams
Journal:  Oncogene       Date:  2008-10-06       Impact factor: 9.867

7.  Impact of cigarette smoking on cancer risk in the European prospective investigation into cancer and nutrition study.

Authors:  Antonio Agudo; Catalina Bonet; Noémie Travier; Carlos A González; Paolo Vineis; H Bas Bueno-de-Mesquita; Dimitrios Trichopoulos; Paolo Boffetta; Françoise Clavel-Chapelon; Marie-Christine Boutron-Ruault; Rudolf Kaaks; Annekatrin Lukanova; Madlen Schütze; Heiner Boeing; Anne Tjonneland; Jytte Halkjaer; Kim Overvad; Christina C Dahm; J Ramon Quirós; María-José Sánchez; Nerea Larrañaga; Carmen Navarro; Eva Ardanaz; Kay-Tee Khaw; Nicholas J Wareham; Timothy J Key; Naomi E Allen; Antonia Trichopoulou; Pagona Lagiou; Domenico Palli; Sabina Sieri; Rosario Tumino; Salvatore Panico; Hendriek Boshuizen; Frederike L Büchner; Petra H M Peeters; Signe Borgquist; Martin Almquist; Göran Hallmans; Ingegerd Johansson; Inger T Gram; Eiliv Lund; Elisabete Weiderpass; Isabelle Romieu; Elio Riboli
Journal:  J Clin Oncol       Date:  2012-11-19       Impact factor: 44.544

8.  Mortality from cancer in relation to smoking: 50 years observations on British doctors.

Authors:  R Doll; R Peto; J Boreham; I Sutherland
Journal:  Br J Cancer       Date:  2005-02-14       Impact factor: 7.640

9.  Signatures of mutational processes in human cancer.

Authors:  Ludmil B Alexandrov; Serena Nik-Zainal; David C Wedge; Samuel A J R Aparicio; Sam Behjati; Andrew V Biankin; Graham R Bignell; Niccolò Bolli; Ake Borg; Anne-Lise Børresen-Dale; Sandrine Boyault; Birgit Burkhardt; Adam P Butler; Carlos Caldas; Helen R Davies; Christine Desmedt; Roland Eils; Jórunn Erla Eyfjörd; John A Foekens; Mel Greaves; Fumie Hosoda; Barbara Hutter; Tomislav Ilicic; Sandrine Imbeaud; Marcin Imielinski; Marcin Imielinsk; Natalie Jäger; David T W Jones; David Jones; Stian Knappskog; Marcel Kool; Sunil R Lakhani; Carlos López-Otín; Sancha Martin; Nikhil C Munshi; Hiromi Nakamura; Paul A Northcott; Marina Pajic; Elli Papaemmanuil; Angelo Paradiso; John V Pearson; Xose S Puente; Keiran Raine; Manasa Ramakrishna; Andrea L Richardson; Julia Richter; Philip Rosenstiel; Matthias Schlesner; Ton N Schumacher; Paul N Span; Jon W Teague; Yasushi Totoki; Andrew N J Tutt; Rafael Valdés-Mas; Marit M van Buuren; Laura van 't Veer; Anne Vincent-Salomon; Nicola Waddell; Lucy R Yates; Jessica Zucman-Rossi; P Andrew Futreal; Ultan McDermott; Peter Lichter; Matthew Meyerson; Sean M Grimmond; Reiner Siebert; Elías Campo; Tatsuhiro Shibata; Stefan M Pfister; Peter J Campbell; Michael R Stratton
Journal:  Nature       Date:  2013-08-14       Impact factor: 49.962

10.  A two-stage theory of carcinogenesis in relation to the age distribution of human cancer.

Authors:  P ARMITAGE; R DOLL
Journal:  Br J Cancer       Date:  1957-06       Impact factor: 7.640
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  4 in total

Review 1.  Computational tools to detect signatures of mutational processes in DNA from tumours: A review and empirical comparison of performance.

Authors:  Hanane Omichessan; Gianluca Severi; Vittorio Perduca
Journal:  PLoS One       Date:  2019-09-12       Impact factor: 3.240

2.  Cutaneous malignant melanoma incidence is strongly associated with European depigmented skin type regardless of ambient ultraviolet radiation levels: evidence from Worldwide population-based data.

Authors:  Wenpeng You; Renata Henneberg; Brendon J Coventry; Maciej Henneberg
Journal:  AIMS Public Health       Date:  2022-03-17

Review 3.  Commonly used estimates of the genetic contribution to disease are subject to the same fallacies as bad luck estimates.

Authors:  Jonas Björk; Tomas Andersson; Anders Ahlbom
Journal:  Eur J Epidemiol       Date:  2019-10-22       Impact factor: 8.082

4.  Objectives, design and main findings until 2020 from the Rotterdam Study.

Authors:  M Arfan Ikram; Guy Brusselle; Mohsen Ghanbari; André Goedegebure; M Kamran Ikram; Maryam Kavousi; Brenda C T Kieboom; Caroline C W Klaver; Robert J de Knegt; Annemarie I Luik; Tamar E C Nijsten; Robin P Peeters; Frank J A van Rooij; Bruno H Stricker; André G Uitterlinden; Meike W Vernooij; Trudy Voortman
Journal:  Eur J Epidemiol       Date:  2020-05-04       Impact factor: 8.082
  4 in total

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