Literature DB >> 306223

Defective neutrophil chemotaxis and raised serum ige levels in a child with recurrent bacterial infections and eczema. Influence of levamisole.

J De Cree, L Emmery, J Timmermans, R Eeckels, W De Cock, H Verhaegen.   

Abstract

A 5 1/2-year-old girl, with a life-long history of recurrent staphylococcal infections and eczematous dermatitis had a defect in polymorphonuclear leucocyte chemotaxis and phagocytosis in autologous serum, a high serum IgE level, and a disturbed T cell function. Levamisole improved all the immunological abnormalities and there was a dramatic clinical improvement. Discontinuation of therapy with levamisole resulted in gradual deterioration.

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Year:  1978        PMID： 306223      PMCID： PMC1545326          DOI： 10.1136/adc.53.2.144

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN： 0003-9888            Impact factor:   3.791


  24 in total

Review 1.  Levamisole in the modulation of the immune response: the current experimental and clinical state.

Authors:  J Symoens; M Rosenthal
Journal:  J Reticuloendothel Soc       Date:  1977-03

2.  Levamisole therapy for cellular immunologic deficiency with high IgE values.

Authors:  R Vanheule; J De Cree; K Adriaenssens; R De Hauwere
Journal:  Acta Paediatr Belg       Date:  1976 Jan-Mar

3.  Effects of levamisole on human monocyte function and immunoprotein receptors.

Authors:  M E Schmidt; S D Douglas
Journal:  Clin Immunol Immunopathol       Date:  1976-11

4.  Defect in neutrophil granulocyte chemotaxis in Job's syndrome of recurrent "cold" staphylococcal abscesses.

Authors:  H R Hill; H D Ochs; P G Quie; R A Clark; H F Pabst; S J Klebanoff; R J Wedgwood
Journal:  Lancet       Date:  1974-09-14       Impact factor: 79.321

5.  Raised serum-IgE levels and defective neutrophil chemotaxis in three children with eczema and recurrent bacterial infections.

Authors:  H R Hill; P G Quie
Journal:  Lancet       Date:  1974-02-09       Impact factor: 79.321

6.  Influence of tetramisole and its optical isomers on the mononuclear phagocytic system. Effect on carbon clearance in mice.

Authors:  J Hoebeke; G Franchi
Journal:  J Reticuloendothel Soc       Date:  1973-09

7.  Restoration by levamisole of histamine-inhibited E rosette formation of T lymphocytes of patients with allergies.

Authors:  W De Cock; J De Crée; H Verhaegen
Journal:  Int Arch Allergy Appl Immunol       Date:  1977

8.  Restoration by levamisole of low E-rosette forming cells in patients suffering from various diseases.

Authors:  H Verhaegen; J De Cree; W De Cock; F Verbruggen
Journal:  Clin Exp Immunol       Date:  1977-02       Impact factor: 4.330

9.  Increase of serum complement levels in cancer patients with progressing tumors.

Authors:  H Verhaegen; W De Cock; J De Cree; F Verbruggen
Journal:  Cancer       Date:  1976-10       Impact factor: 6.860

10.  In vitro phagocytosis of Candida albicans by peripheral polymorphonuclear neutrophils of patients with recurrent infections:Case reports of serum-dependent abnormalities.

Authors:  H Verhaegen; W de Cock; J de Cree
Journal:  Biomedicine       Date:  1976-06
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  8 in total

Review 1.  Human hyper-IgE syndrome: singular or plural?

Authors:  Qian Zhang; Bertrand Boisson; Vivien Béziat; Anne Puel; Jean-Laurent Casanova
Journal:  Mamm Genome       Date:  2018-08-09       Impact factor: 2.957

2.  The in vitro evaluation of certain neutrophil and lymphocyte functions following the ingestion of 150 mg oral dose of levamisole: assessment of the extent and duration of stimulation of neutrophil chemotaxis, protein iodination and lymphocyte transformation.

Authors:  R Anderson; R Oosthuizen; A Theron; A J Van Rensburg
Journal:  Clin Exp Immunol       Date:  1979-03       Impact factor: 4.330

3.  Transfer factor therapy in hyperimmunoglobulinaemia E syndrome.

Authors:  H H Kesarwala; R V Prasad; R Szep; E Oldman; S Lane; P S Papageorgiou
Journal:  Clin Exp Immunol       Date:  1979-06       Impact factor: 4.330

4.  Defective neutrophil chemotaxis and bactericidal power in a child with hyperimmunoglobulinemia E.

Authors:  F Patrone; F Dallegri; A Rebora
Journal:  Eur J Pediatr       Date:  1979-03-01       Impact factor: 3.183

5.  Delayed separation of the umbilical cord, severe widespread infections, and immunodeficiency.

Authors:  J G Bissenden; M R Haeney; M J Tarlow; R A Thompson
Journal:  Arch Dis Child       Date:  1981-05       Impact factor: 3.791

6.  A child with atopic features, raised serum IgE, and recurrent infection treated with levamisole.

Authors:  L Businco; F Laurenti; P Rossi; E Galli; F Aiuti
Journal:  Arch Dis Child       Date:  1981-01       Impact factor: 3.791

7.  Immunological observations before and after successful treatment of chronic mucocutaneous candidiasis with ketoconazole and transfer factor.

Authors:  L Corbeel; J L Ceuppens; G Van den Berghe; H Claeys; M Casteels-Van Daele
Journal:  Eur J Pediatr       Date:  1984-11       Impact factor: 3.183

8.  [The Buckley syndrome: recurring, severe staphylococcal infections, eczema and hyperimmunoglobulinemia E. (author's transl)].

Authors:  S Däumling; D Buriot; P H Trung; C Griscelli; M C Lalama; B H Belohradsky
Journal:  Infection       Date:  1980       Impact factor: 3.553
  8 in total

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