Literature DB >> 30620904

FISHing for β Cells.

Laura I Hudish1, David S Lorberbaum1, Lori Sussel2.   

Abstract

β cell heterogeneity has emerged as an important contributor to islet function, with potential implications for diabetes. Using an optimized smFISH technique in intact islets, Farack et al. (2018) identify in the islet core an endocrine cell population of "extreme" β cells with distinct molecular properties.
Copyright © 2018 Elsevier Inc. All rights reserved.

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Year:  2019        PMID： 30620904      PMCID： PMC6961780          DOI： 10.1016/j.devcel.2018.12.007

Source DB:  PubMed          Journal:  Dev Cell        ISSN： 1534-5807            Impact factor:   12.270


  10 in total

1.  Identification of proliferative and mature β-cells in the islets of Langerhans.

Authors:  Erik Bader; Adriana Migliorini; Moritz Gegg; Noah Moruzzi; Jantje Gerdes; Sara S Roscioni; Mostafa Bakhti; Elisabeth Brandl; Martin Irmler; Johannes Beckers; Michaela Aichler; Annette Feuchtinger; Christin Leitzinger; Hans Zischka; Rui Wang-Sattler; Martin Jastroch; Matthias Tschöp; Fausto Machicao; Harald Staiger; Hans-Ulrich Häring; Helena Chmelova; Julie A Chouinard; Nikolay Oskolkov; Olle Korsgren; Stephan Speier; Heiko Lickert
Journal:  Nature       Date:  2016-07-11       Impact factor: 49.962

2.  Transcriptional Heterogeneity of Beta Cells in the Intact Pancreas.

Authors:  Lydia Farack; Matan Golan; Adi Egozi; Nili Dezorella; Keren Bahar Halpern; Shani Ben-Moshe; Immacolata Garzilli; Beáta Tóth; Lior Roitman; Valery Krizhanovsky; Shalev Itzkovitz
Journal:  Dev Cell       Date:  2018-11-29       Impact factor: 12.270

3.  Stimulation of insulin secretion reveals heterogeneity of pancreatic B cells in vivo.

Authors:  Y Stefan; P Meda; M Neufeld; L Orci
Journal:  J Clin Invest       Date:  1987-07       Impact factor: 14.808

4.  Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets.

Authors:  Talitha van der Meulen; Alex M Mawla; Michael R DiGruccio; Michael W Adams; Vera Nies; Sophie Dólleman; Siming Liu; Amanda M Ackermann; Elena Cáceres; Anna E Hunter; Klaus H Kaestner; Cynthia J Donaldson; Mark O Huising
Journal:  Cell Metab       Date:  2017-04-04       Impact factor: 27.287

5.  Fluctuation localization imaging-based fluorescence in situ hybridization (fliFISH) for accurate detection and counting of RNA copies in single cells.

Authors:  Yi Cui; Dehong Hu; Lye Meng Markillie; William B Chrisler; Matthew J Gaffrey; Charles Ansong; Lori Sussel; Galya Orr
Journal:  Nucleic Acids Res       Date:  2018-01-25       Impact factor: 16.971

6.  Single-Cell Transcriptomics of the Human Endocrine Pancreas.

Authors:  Yue J Wang; Jonathan Schug; Kyoung-Jae Won; Chengyang Liu; Ali Naji; Dana Avrahami; Maria L Golson; Klaus H Kaestner
Journal:  Diabetes       Date:  2016-06-30       Impact factor: 9.461

7.  Human islets contain four distinct subtypes of β cells.

Authors:  Craig Dorrell; Jonathan Schug; Pamela S Canaday; Holger A Russ; Branden D Tarlow; Maria T Grompe; Tamara Horton; Matthias Hebrok; Philip R Streeter; Klaus H Kaestner; Markus Grompe
Journal:  Nat Commun       Date:  2016-07-11       Impact factor: 14.919

Review 8.  Heterogeneity of the Pancreatic Beta Cell.

Authors:  Giselle Dominguez Gutierrez; Jesper Gromada; Lori Sussel
Journal:  Front Genet       Date:  2017-03-06       Impact factor: 4.599

9.  Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose.

Authors:  Natalie R Johnston; Ryan K Mitchell; Elizabeth Haythorne; Maria Paiva Pessoa; Francesca Semplici; Jorge Ferrer; Lorenzo Piemonti; Piero Marchetti; Marco Bugliani; Domenico Bosco; Ekaterine Berishvili; Philip Duncanson; Michael Watkinson; Johannes Broichhagen; Dirk Trauner; Guy A Rutter; David J Hodson
Journal:  Cell Metab       Date:  2016-07-21       Impact factor: 27.287

10.  New Understanding of β-Cell Heterogeneity and In Situ Islet Function.

Authors:  Richard K P Benninger; David J Hodson
Journal:  Diabetes       Date:  2018-04       Impact factor: 9.461
  10 in total

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