Literature DB >> 30620720

Regulation of GDNF expression in Sertoli cells.

Parag A Parekh1, Thomas X Garcia2,3, Marie-Claude Hofmann1.   

Abstract

Sertoli cells regulate male germ cell proliferation and differentiation and are a critical component of the spermatogonial stem cell (SSC) niche, where homeostasis is maintained by the interplay of several signaling pathways and growth factors. These factors are secreted by Sertoli cells located within the seminiferous epithelium, and by interstitial cells residing between the seminiferous tubules. Sertoli cells and peritubular myoid cells produce glial cell line-derived neurotrophic factor (GDNF), which binds to the RET/GFRA1 receptor complex at the surface of undifferentiated spermatogonia. GDNF is known for its ability to drive SSC self-renewal and proliferation of their direct cell progeny. Even though the effects of GDNF are well studied, our understanding of the regulation its expression is still limited. The purpose of this review is to discuss how GDNF expression in Sertoli cells is modulated within the niche, and how these mechanisms impact germ cell homeostasis.

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Year:  2019        PMID： 30620720      PMCID： PMC6602878          DOI： 10.1530/REP-18-0239

Source DB:  PubMed          Journal:  Reproduction        ISSN： 1470-1626            Impact factor:   3.906


  157 in total

1.  Distribution of GFRA1-expressing spermatogonia in adult mouse testis.

Authors:  Margherita Grasso; Andrea Fuso; Lisa Dovere; Dirk G de Rooij; Mario Stefanini; Carla Boitani; Elena Vicini
Journal:  Reproduction       Date:  2011-12-05       Impact factor: 3.906

2.  Renal and neuronal abnormalities in mice lacking GDNF.

Authors:  M W Moore; R D Klein; I Fariñas; H Sauer; M Armanini; H Phillips; L F Reichardt; A M Ryan; K Carver-Moore; A Rosenthal
Journal:  Nature       Date:  1996-07-04       Impact factor: 49.962

3.  Two classes of spermatogonial stem cells in the monkey (Cercopithecus aethiops).

Authors:  Y Clermont
Journal:  Am J Anat       Date:  1969-09

4.  Growth factors essential for self-renewal and expansion of mouse spermatogonial stem cells.

Authors:  Hiroshi Kubota; Mary R Avarbock; Ralph L Brinster
Journal:  Proc Natl Acad Sci U S A       Date:  2004-11-01       Impact factor: 11.205

5.  Morphological alterations in the peripheral and central nervous systems of mice lacking glial cell line-derived neurotrophic factor (GDNF): immunohistochemical studies.

Authors:  A C Granholm; N Srivastava; J L Mott; S Henry; M Henry; H Westphal; J G Pichel; L Shen; B J Hoffer
Journal:  J Neurosci       Date:  1997-02-01       Impact factor: 6.167

6.  Mammalian target of rapamycin complex 1 (mTORC1) Is required for mouse spermatogonial differentiation in vivo.

Authors:  Jonathan T Busada; Bryan A Niedenberger; Ellen K Velte; Brett D Keiper; Christopher B Geyer
Journal:  Dev Biol       Date:  2015-08-05       Impact factor: 3.582

7.  Neurogenin3 delineates the earliest stages of spermatogenesis in the mouse testis.

Authors:  Shosei Yoshida; Ayumi Takakura; Kazuyuki Ohbo; Kuniya Abe; Junko Wakabayashi; Masayuki Yamamoto; Toshio Suda; Yo-Ichi Nabeshima
Journal:  Dev Biol       Date:  2004-05-15       Impact factor: 3.582

Review 8.  Structure and physiology of the RET receptor tyrosine kinase.

Authors:  Carlos F Ibáñez
Journal:  Cold Spring Harb Perspect Biol       Date:  2013-02-01       Impact factor: 10.005

9.  Constitutive activation of NOTCH1 signaling in Sertoli cells causes gonocyte exit from quiescence.

Authors:  Thomas Xavier Garcia; Tony DeFalco; Blanche Capel; Marie-Claude Hofmann
Journal:  Dev Biol       Date:  2013-02-04       Impact factor: 3.582

Review 10.  Functional assessment of spermatogonial stem cell purity in experimental cell populations.

Authors:  Tessa Lord; Jon M Oatley
Journal:  Stem Cell Res       Date:  2018-04-03       Impact factor: 2.020
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  11 in total

1.  Mapping molecular pathways for embryonic Sertoli cells derivation based on differentiation model of mouse embryonic stem cells.

Authors:  Chenze Xu; Yichen Dai; Ali Mohsin; Haifeng Hang; Yingping Zhuang; Meijin Guo
Journal:  Stem Cell Res Ther       Date:  2020-02-26       Impact factor: 6.832

2.  EGF, GDNF, and IGF-1 influence the proliferation and stemness of ovine spermatogonial stem cells in vitro.

Authors:  B K Binsila; S Selvaraju; S K Ghosh; L Ramya; A Arangasamy; R Ranjithkumaran; R Bhatta
Journal:  J Assist Reprod Genet       Date:  2020-08-21       Impact factor: 3.412

3.  Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia.

Authors:  Daniel R Garton; Ana R Montaño-Rodríguez; Soophie Olfat; Kärt Mätlik; Feride Eren; Laoise Casserly; Anastasios Damdimopoulos; Anne Panhelainen; L Lauriina Porokuokka; Jaakko J Kopra; Giorgio Turconi; Nadine Schweizer; Erika Bereczki; Fredrik Piehl; Göran Engberg; Simon Cervenka; T Petteri Piepponen; Fu-Ping Zhang; Petra Sipilä; Johan Jakobsson; Carl M Sellgren; Sophie Erhardt; Jaan-Olle Andressoo
Journal:  Mol Psychiatry       Date:  2022-05-26       Impact factor: 15.992

4.  Follicle-stimulating hormone-mediated decline in miR-92a-3p expression in pubertal mice Sertoli cells is crucial for germ cell differentiation and fertility.

Authors:  Alka Gupta; Amandeep Vats; Anindita Ghosal; Kamal Mandal; Rajesh Sarkar; Indrashis Bhattacharya; Sanjeev Das; Rahul Pal; Subeer S Majumdar
Journal:  Cell Mol Life Sci       Date:  2022-02-18       Impact factor: 9.261

Review 5.  Regulation of spermatogonial stem cell self-renewal and proliferation in mammals.

Authors:  Bang-Hong Wei; Shuang-Li Hao; Wan-Xi Yang
Journal:  Histol Histopathol       Date:  2022-04-26       Impact factor: 2.130

6.  Gdnf Acts as a Germ Cell-Derived Growth Factor and Regulates the Zebrafish Germ Stem Cell Niche in Autocrine- and Paracrine-Dependent Manners.

Authors:  Lucas B Doretto; Arno J Butzge; Rafael T Nakajima; Emanuel R M Martinez; Beatriz Marques de Souza; Maira da Silva Rodrigues; Ivana F Rosa; Juliana M B Ricci; Aldo Tovo-Neto; Daniel F Costa; Guilherme Malafaia; Changwei Shao; Rafael H Nóbrega
Journal:  Cells       Date:  2022-04-11       Impact factor: 7.666

Review 7.  Recent Research Advances in Mitosis during Mammalian Gametogenesis.

Authors:  Jia-Hao Wang; Yan Li; Shou-Long Deng; Yi-Xun Liu; Zheng-Xing Lian; Kun Yu
Journal:  Cells       Date:  2019-06-10       Impact factor: 6.600

8.  Low retinoic acid levels mediate regionalization of the Sertoli valve in the terminal segment of mouse seminiferous tubules.

Authors:  Kasane Imura-Kishi; Aya Uchida; Naoki Tsunekawa; Hitomi Suzuki; Hinako M Takase; Yoshikazu Hirate; Masami Kanai-Azuma; Ryuji Hiramatsu; Masamichi Kurohmaru; Yoshiakira Kanai
Journal:  Sci Rep       Date:  2021-01-13       Impact factor: 4.379

9.  hnRNPU in Sertoli cells cooperates with WT1 and is essential for testicular development by modulating transcriptional factors Sox8/9.

Authors:  Yujiao Wen; Xixiang Ma; Xiaoli Wang; Fengli Wang; Juan Dong; Yanqing Wu; Chunyu Lv; Kuan Liu; Yan Zhang; Zhibing Zhang; Shuiqiao Yuan
Journal:  Theranostics       Date:  2021-10-25       Impact factor: 11.556

10.  Effect of EPA on Neonatal Pig Sertoli Cells "In Vitro": A Possible Treatment to Help Maintain Fertility in Pre-Pubertal Boys Undergoing Treatment With Gonado-Toxic Therapies.

Authors:  Iva Arato; Veronica Ceccarelli; Francesca Mancuso; Catia Bellucci; Cinzia Lilli; Piero Ferolla; Katia Perruccio; Alessandro D'Arpino; Maria Chiara Aglietti; Riccardo Calafiore; Don F Cameron; Mario Calvitti; Tiziano Baroni; Alba Vecchini; Giovanni Luca
Journal:  Front Endocrinol (Lausanne)       Date:  2021-05-20       Impact factor: 5.555
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