Literature DB >> 3062016

High-performance liquid chromatography of porphyrins.

C K Lim1, F M Li, T J Peters.   

Abstract

Techniques for the analysis of porphyrins in the biomedical fields are reviewed. The emphasis is on high-performance liquid chromatography and its aspplications in: (1) the quantitative analysis of porphyrins in blood, urine and faeces; (2) qualitative porphyrin profiles in normal subjects and in the porphyrias; (3) assay of haem biosynthetic enzyme activities and (4) resolution of type isomers of porphyrins and porphyrinogens. Detection systems, quantitation methods, peak identification and sample preparation procedures are discussed.

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Year:  1988        PMID： 3062016     DOI： 10.1016/s0378-4347(00)83869-4

Source DB:  PubMed          Journal:  J Chromatogr


  7 in total

1.  Insight into GATA1 transcriptional activity through interrogation of cis elements disrupted in human erythroid disorders.

Authors:  Aoi Wakabayashi; Jacob C Ulirsch; Leif S Ludwig; Claudia Fiorini; Makiko Yasuda; Avik Choudhuri; Patrick McDonel; Leonard I Zon; Vijay G Sankaran
Journal:  Proc Natl Acad Sci U S A       Date:  2016-04-04       Impact factor: 11.205

2.  Mutation in human CLPX elevates levels of δ-aminolevulinate synthase and protoporphyrin IX to promote erythropoietic protoporphyria.

Authors:  Yvette Y Yien; Sarah Ducamp; Lisa N van der Vorm; Julia R Kardon; Hana Manceau; Caroline Kannengiesser; Hector A Bergonia; Martin D Kafina; Zoubida Karim; Laurent Gouya; Tania A Baker; Hervé Puy; John D Phillips; Gaël Nicolas; Barry H Paw
Journal:  Proc Natl Acad Sci U S A       Date:  2017-09-05       Impact factor: 11.205

3.  Isolation and characterization of protoporphyrin glycoconjugates from rat harderian gland by HPLC, capillary electrophoresis and HPLC/electrospray ionization MS.

Authors:  C K Lim; M A Razzaque; J Luo; P B Farmer
Journal:  Biochem J       Date:  2000-05-01       Impact factor: 3.857

4.  Effects of expression of hemA and hemB genes on production of porphyrin in Propionibacterium freudenreichii.

Authors:  Yongzhe Piao; Pornpimon Kiatpapan; Mitsuo Yamashita; Yoshikatsu Murooka
Journal:  Appl Environ Microbiol       Date:  2004-12       Impact factor: 4.792

5.  Uroporphyrinogen III synthase knock-in mice have the human congenital erythropoietic porphyria phenotype, including the characteristic light-induced cutaneous lesions.

Authors:  David F Bishop; Annika Johansson; Robert Phelps; Amr A Shady; Maria C M Ramirez; Makiko Yasuda; Andres Caro; Robert J Desnick
Journal:  Am J Hum Genet       Date:  2006-02-09       Impact factor: 11.025

6.  Direct assay of enzymes in heme biosynthesis for the detection of porphyrias by tandem mass spectrometry. Porphobilinogen deaminase.

Authors:  Yuesong Wang; C Ronald Scott; Michael H Gelb; Frantisek Turecek
Journal:  Anal Chem       Date:  2008-02-23       Impact factor: 6.986

7.  Feline acute intermittent porphyria: a phenocopy masquerading as an erythropoietic porphyria due to dominant and recessive hydroxymethylbilane synthase mutations.

Authors:  Sonia Clavero; David F Bishop; Mark E Haskins; Urs Giger; Raili Kauppinen; Robert J Desnick
Journal:  Hum Mol Genet       Date:  2009-11-24       Impact factor: 6.150
  7 in total

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