Literature DB >> 30620027

Transition metal substituted sandwich-type polyoxometalates with a strong metal-C (imidazole) bond as anticancer agents.

Hongxia Zhao1, Li Tao, Fengmin Zhang, Ying Zhang, Yanqing Liu, Hongjie Xu, Guowang Diao, Lubin Ni.   

Abstract

Two novel sandwich-type polyoxometalates {Na0.7M5.3(H2O)2(imi)2(Himi)(SbW9O33)2}6- (M = NiII (1), CoII (2), imi = imidazole) containing a strong M-Cimi bond were synthesized by a tetragonal cluster [Na2Sb8W36O132(H2O)4]22- {Sb8W36} precursor. Compound 1 was highly cytotoxic against gastric cancer cells by arresting the cell cycle in the S-phase and inducing cell apoptosis.

Entities:  

Mesh:

Substances:

Year:  2019        PMID: 30620027     DOI: 10.1039/c8cc07884j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  Evaluation of the Anticancer Activities of Novel Transition Metal Complexes with Berenil and Nitroimidazole.

Authors:  Robert Czarnomysy; Dominika Radomska; Anna Muszyńska; Justyna Magdalena Hermanowicz; Izabela Prokop; Anna Bielawska; Krzysztof Bielawski
Journal:  Molecules       Date:  2020-06-21       Impact factor: 4.411

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.