Literature DB >> 30617356

Tumor targeting with DGEA peptide ligands: a new aromatic peptide amphiphile for imaging cancers.

Fu-Kai Zhan1, Jyun-Cheng Liu2, Bill Cheng1, Yen-Chu Liu1, Tsung-Sheng Lai1, Hsin-Chieh Lin1, Mei-Yu Yeh2.   

Abstract

We report a novel fluorescent bioprobe, tetraphenylethylene-Phe-Asp-Gly-Glu-Ala (TPE-FDGEA), and its self-assembly behavior, photophysical properties, and biocompatibility. The hydrogelator TPE-FDGEA exhibited aggregation-induced emission characteristics, which facilitated imaging of PC-3 human prostate cancer cells, thereby demonstrating the utility of such fluorescent probes for specific labeling of target cells in vitro.

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Year:  2019        PMID： 30617356     DOI： 10.1039/c8cc08679f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  2 in total

1.  Efficient Hydro- and Organogelation by Minimalistic Diketopiperazines Containing a Highly Insoluble Aggregation-Induced, Blue-Shifted Emission Luminophore*.

Authors:  Martin Molkenthin; Werner M Nau; Boris J Nachtsheim
Journal:  Chemistry       Date:  2021-10-22       Impact factor: 5.020

2.  Thiophene-containing tetraphenylethene derivatives with different aggregation-induced emission (AIE) and mechanofluorochromic characteristics.

Authors:  Ya Yin; Zhao Chen; Yue Yang; Gang Liu; Congbin Fan; Shouzhi Pu
Journal:  RSC Adv       Date:  2019-08-06       Impact factor: 4.036
  2 in total

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