Literature DB >> 30617094

Adjuvant β-Lactam Therapy Combined with Vancomycin for Methicillin-Resistant Staphylococcus aureus Bacteremia: Does β-Lactam Class Matter?

Thomas J Dilworth1, Anthony M Casapao2, Omar M Ibrahim3, David M Jacobs4, Dana R Bowers5, Nicholas D Beyda6, Renee-Claude Mercier7.   

Abstract

We analyzed the impact of vancomycin (VAN) combined with adjuvant β-lactam therapy (Combo) on persistent (≥5 days) methicillin-resistant Staphylococcus aureus bacteremia versus VAN alone by using pooled data from two previously published observational studies (n = 156). Combo was inversely associated with persistent bacteremia (adjusted odds ratio, 0.460; 95% confidence interval, 0.229 to 0.923). Acute kidney injury was more common with Combo than with VAN (18.9% and 7.6%, respectively; P = 0.062).
Copyright © 2019 American Society for Microbiology.

Entities:  

Keywords:  bacteremia; combination therapy; methicillin-resistant Staphylococcus aureuszzm321990; vancomycin; β-lactam

Mesh：

Substances：

Year:  2019        PMID： 30617094      PMCID： PMC6395910          DOI： 10.1128/AAC.02211-18

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  4 in total

Review 1.  Focusing the Lens on the CAMERA Concepts: Early Combination β-Lactam and Vancomycin Therapy in Methicillin-Resistant Staphylococcus aureus Bacteremia.

Authors:  H Andrew Wilsey; Donna R Burgess; David S Burgess
Journal:  Antimicrob Agents Chemother       Date:  2020-06-23       Impact factor: 5.191

2.  Multicenter Study of the Real-World Use of Ceftaroline versus Vancomycin for Acute Bacterial Skin and Skin Structure Infections.

Authors:  T D Trinh; S C J Jorgensen; E J Zasowski; K C Claeys; A M Lagnf; S J Estrada; D J Delaportes; V Huang; K P Klinker; K S Kaye; S L Davis; M J Rybak
Journal:  Antimicrob Agents Chemother       Date:  2019-10-22       Impact factor: 5.191

3.  Cytokine measurements add value to clinical variables in predicting outcomes for Staphylococcus aureus bacteremia.

Authors:  Karen Tan; Emi Minejima; Mimi Lou; Wendy J Mack; Paul Nieberg; Annie Wong-Beringer
Journal:  BMC Infect Dis       Date:  2021-04-05       Impact factor: 3.090

4.  Subinhibitory Concentrations of Antibiotics Exacerbate Staphylococcal Infection by Inducing Bacterial Virulence.

Authors:  Peng Gao; Yuanxin Wei; Rachel Evelyn Wan; Ka Wing Wong; Ho Ting Venice Iu; Sherlock Shing Chiu Tai; Yongli Li; Hin Cheung Bill Yam; Pradeep Halebeedu Prakash; Jonathan Hon Kwan Chen; Pak Leung Ho; Kwok Yung Yuen; Julian Davies; Richard Yi Tsun Kao
Journal:  Microbiol Spectr       Date:  2022-06-27
  4 in total

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