Literature DB >> 30614191

Assessment of circulating tumor DNA in pediatric solid tumors: The promise of liquid biopsies.

Samuel D Abbou1,2, David S Shulman1, Steven G DuBois1, Brian D Crompton1,3.   

Abstract

Circulating tumor DNA can be detected in the blood and body fluids of patients using ultrasensitive technologies, which have the potential to improve cancer diagnosis, risk stratification, noninvasive tumor profiling, and tracking of treatment response and disease recurrence. As we begin to apply "liquid biopsy" strategies in children with cancer, it is important to tailor our efforts to the unique genomic features of these tumors and address the technical and logistical challenges of integrating biomarker testing. This article reviews the literature demonstrating the feasibility of applying liquid biopsy to pediatric solid malignancies and suggests new directions for future studies.
© 2019 Wiley Periodicals, Inc.

Entities:  

Keywords:  circulating tumor DNA; digital PCR; liquid biopsy; next-generation sequencing; pediatric cancer

Mesh：

Substances：

Year:  2019        PMID： 30614191      PMCID： PMC6550461          DOI： 10.1002/pbc.27595

Source DB:  PubMed          Journal:  Pediatr Blood Cancer        ISSN： 1545-5009            Impact factor:   3.167


  104 in total

1.  Noninvasive monitoring of infection and rejection after lung transplantation.

Authors:  Iwijn De Vlaminck; Lance Martin; Michael Kertesz; Kapil Patel; Mark Kowarsky; Calvin Strehl; Garrett Cohen; Helen Luikart; Norma F Neff; Jennifer Okamoto; Mark R Nicolls; David Cornfield; David Weill; Hannah Valantine; Kiran K Khush; Stephen R Quake
Journal:  Proc Natl Acad Sci U S A       Date:  2015-10-12       Impact factor: 11.205

2.  The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes.

Authors:  Robert Huether; Li Dong; Xiang Chen; Gang Wu; Matthew Parker; Lei Wei; Jing Ma; Michael N Edmonson; Erin K Hedlund; Michael C Rusch; Sheila A Shurtleff; Heather L Mulder; Kristy Boggs; Bhavin Vadordaria; Jinjun Cheng; Donald Yergeau; Guangchun Song; Jared Becksfort; Gordon Lemmon; Catherine Weber; Zhongling Cai; Jinjun Dang; Michael Walsh; Amanda L Gedman; Zachary Faber; John Easton; Tanja Gruber; Richard W Kriwacki; Janet F Partridge; Li Ding; Richard K Wilson; Elaine R Mardis; Charles G Mullighan; Richard J Gilbertson; Suzanne J Baker; Gerard Zambetti; David W Ellison; Jinghui Zhang; James R Downing
Journal:  Nat Commun       Date:  2014-04-08       Impact factor: 14.919

3.  Quantitative and sensitive detection of rare mutations using droplet-based microfluidics.

Authors:  Deniz Pekin; Yousr Skhiri; Jean-Christophe Baret; Delphine Le Corre; Linas Mazutis; Chaouki Ben Salem; Florian Millot; Abdeslam El Harrak; J Brian Hutchison; Jonathan W Larson; Darren R Link; Pierre Laurent-Puig; Andrew D Griffiths; Valérie Taly
Journal:  Lab Chip       Date:  2011-05-19       Impact factor: 6.799

4.  Genomic Copy Number Profiling Using Circulating Free Tumor DNA Highlights Heterogeneity in Neuroblastoma.

Authors:  Mathieu Chicard; Sandrine Boyault; Leo Colmet Daage; Wilfrid Richer; David Gentien; Gaelle Pierron; Eve Lapouble; Angela Bellini; Nathalie Clement; Isabelle Iacono; Stéphanie Bréjon; Marjorie Carrere; Cécile Reyes; Toby Hocking; Virginie Bernard; Michel Peuchmaur; Nadège Corradini; Cécile Faure-Conter; Carole Coze; Dominique Plantaz; Anne Sophie Defachelles; Estelle Thebaud; Marion Gambart; Frédéric Millot; Dominique Valteau-Couanet; Jean Michon; Alain Puisieux; Olivier Delattre; Valérie Combaret; Gudrun Schleiermacher
Journal:  Clin Cancer Res       Date:  2016-07-20       Impact factor: 12.531

5.  Circulating Tumor DNA Reveals Clinically Actionable Somatic Genome of Metastatic Bladder Cancer.

Authors:  Gillian Vandekerkhove; Tilman Todenhöfer; Matti Annala; Werner J Struss; Amanda Wong; Kevin Beja; Elie Ritch; Sonal Brahmbhatt; Stanislav V Volik; Jörg Hennenlotter; Matti Nykter; Kim N Chi; Scott North; Arnulf Stenzl; Colin C Collins; Bernhard J Eigl; Peter C Black; Alexander W Wyatt
Journal:  Clin Cancer Res       Date:  2017-07-31       Impact factor: 12.531

6.  High fragmentation characterizes tumour-derived circulating DNA.

Authors:  Florent Mouliere; Bruno Robert; Erika Arnau Peyrotte; Maguy Del Rio; Marc Ychou; Franck Molina; Celine Gongora; Alain R Thierry
Journal:  PLoS One       Date:  2011-09-06       Impact factor: 3.240

7.  Detection of tumor ALK status in neuroblastoma patients using peripheral blood.

Authors:  Valérie Combaret; Isabelle Iacono; Angela Bellini; Stéphanie Bréjon; Virginie Bernard; Aurélien Marabelle; Carole Coze; Gaelle Pierron; Eve Lapouble; Gudrun Schleiermacher; Jean Yves Blay
Journal:  Cancer Med       Date:  2015-02-04       Impact factor: 4.452

8.  Gefitinib treatment in EGFR mutated caucasian NSCLC: circulating-free tumor DNA as a surrogate for determination of EGFR status.

Authors:  Jean-Yves Douillard; Gyula Ostoros; Manuel Cobo; Tudor Ciuleanu; Rebecca Cole; Gael McWalter; Jill Walker; Simon Dearden; Alan Webster; Tsveta Milenkova; Rose McCormack
Journal:  J Thorac Oncol       Date:  2014-09       Impact factor: 15.609

9.  Sequenza: allele-specific copy number and mutation profiles from tumor sequencing data.

Authors:  F Favero; T Joshi; A M Marquard; N J Birkbak; M Krzystanek; Q Li; Z Szallasi; A C Eklund
Journal:  Ann Oncol       Date:  2014-10-15       Impact factor: 32.976

10.  Mutational heterogeneity in cancer and the search for new cancer-associated genes.

Authors:  Michael S Lawrence; Petar Stojanov; Paz Polak; Gregory V Kryukov; Kristian Cibulskis; Andrey Sivachenko; Scott L Carter; Chip Stewart; Craig H Mermel; Steven A Roberts; Adam Kiezun; Peter S Hammerman; Aaron McKenna; Yotam Drier; Lihua Zou; Alex H Ramos; Trevor J Pugh; Nicolas Stransky; Elena Helman; Jaegil Kim; Carrie Sougnez; Lauren Ambrogio; Elizabeth Nickerson; Erica Shefler; Maria L Cortés; Daniel Auclair; Gordon Saksena; Douglas Voet; Michael Noble; Daniel DiCara; Pei Lin; Lee Lichtenstein; David I Heiman; Timothy Fennell; Marcin Imielinski; Bryan Hernandez; Eran Hodis; Sylvan Baca; Austin M Dulak; Jens Lohr; Dan-Avi Landau; Catherine J Wu; Jorge Melendez-Zajgla; Alfredo Hidalgo-Miranda; Amnon Koren; Steven A McCarroll; Jaume Mora; Brian Crompton; Robert Onofrio; Melissa Parkin; Wendy Winckler; Kristin Ardlie; Stacey B Gabriel; Charles W M Roberts; Jaclyn A Biegel; Kimberly Stegmaier; Adam J Bass; Levi A Garraway; Matthew Meyerson; Todd R Golub; Dmitry A Gordenin; Shamil Sunyaev; Eric S Lander; Gad Getz
Journal:  Nature       Date:  2013-06-16       Impact factor: 49.962
View more
  10 in total

1.  Genetic changes associated with relapse in favorable histology Wilms tumor: A Children's Oncology Group AREN03B2 study.

Authors:  Samantha Gadd; Vicki Huff; Andrew D Skol; Lindsay A Renfro; Conrad V Fernandez; Elizabeth A Mullen; Corbin D Jones; Katherine A Hoadley; Kai Lee Yap; Nilsa C Ramirez; Sheena Aris; Quy H Phung; Elizabeth J Perlman
Journal:  Cell Rep Med       Date:  2022-05-25

2.  Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden.

Authors:  Peter Peneder; Adrian M Stütz; Didier Surdez; Manuela Krumbholz; Sabine Semper; Mathieu Chicard; Nathan C Sheffield; Gaelle Pierron; Eve Lapouble; Marcus Tötzl; Bekir Ergüner; Daniele Barreca; André F Rendeiro; Abbas Agaimy; Heidrun Boztug; Gernot Engstler; Michael Dworzak; Marie Bernkopf; Sabine Taschner-Mandl; Inge M Ambros; Ola Myklebost; Perrine Marec-Bérard; Susan Ann Burchill; Bernadette Brennan; Sandra J Strauss; Jeremy Whelan; Gudrun Schleiermacher; Christiane Schaefer; Uta Dirksen; Caroline Hutter; Kjetil Boye; Peter F Ambros; Olivier Delattre; Markus Metzler; Christoph Bock; Eleni M Tomazou
Journal:  Nat Commun       Date:  2021-05-28       Impact factor: 14.919

3.  A Targeted Gene Panel for Circulating Tumor DNA Sequencing in Neuroblastoma.

Authors:  Flora Cimmino; Vito Alessandro Lasorsa; Simona Vetrella; Achille Iolascon; Mario Capasso
Journal:  Front Oncol       Date:  2020-12-14       Impact factor: 6.244

Review 4.  Liquid biopsies in pediatric oncology: opportunities and obstacles.

Authors:  R Taylor Sundby; Alex Pan; Jack F Shern
Journal:  Curr Opin Pediatr       Date:  2022-02-01       Impact factor: 2.893

5.  Circulating Tumor DNA as a Biomarker in Patients With Stage III and IV Wilms Tumor: Analysis From a Children's Oncology Group Trial, AREN0533.

Authors:  Laura M Madanat-Harjuoja; Lindsay A Renfro; Kelly Klega; Brett Tornwall; Aaron R Thorner; Anwesha Nag; David Dix; Jeffrey S Dome; Lisa R Diller; Conrad V Fernandez; Elizabeth A Mullen; Brian D Crompton
Journal:  J Clin Oncol       Date:  2022-05-17       Impact factor: 50.717

6.  Clinical implementation of plasma cell-free circulating tumor DNA quantification by digital droplet PCR for the monitoring of Ewing sarcoma in children and adolescents.

Authors:  Markus G Seidel; Karl Kashofer; Tina Moser; Andrea Thueringer; Bernadette Liegl-Atzwanger; Andreas Leithner; Joanna Szkandera; Martin Benesch; Amin El-Heliebi; Ellen Heitzer
Journal:  Front Pediatr       Date:  2022-08-15       Impact factor: 3.569

7.  Revised Neuroblastoma Risk Classification System: A Report From the Children's Oncology Group.

Authors:  Meredith S Irwin; Arlene Naranjo; Fan F Zhang; Susan L Cohn; Wendy B London; Julie M Gastier-Foster; Nilsa C Ramirez; Ruthann Pfau; Shalini Reshmi; Elizabeth Wagner; Jed Nuchtern; Shahab Asgharzadeh; Hiroyuki Shimada; John M Maris; Rochelle Bagatell; Julie R Park; Michael D Hogarty
Journal:  J Clin Oncol       Date:  2021-07-28       Impact factor: 50.717

8.  An evolutionary framework for treating pediatric sarcomas.

Authors:  Damon R Reed; Jonathan Metts; Mariyah Pressley; Brooke L Fridley; Masanori Hayashi; Michael S Isakoff; David M Loeb; Rikesh Makanji; Ryan D Roberts; Matteo Trucco; Lars M Wagner; Mark G Alexandrow; Robert A Gatenby; Joel S Brown
Journal:  Cancer       Date:  2020-03-16       Impact factor: 6.860

9.  BRAF V600E Detection in Liquid Biopsies from Pediatric Central Nervous System Tumors.

Authors:  Noemi García-Romero; Josefa Carrión-Navarro; Pilar Areal-Hidalgo; Ana Ortiz de Mendivil; Adriá Asensi-Puig; Rodrigo Madurga; Rocio Núñez-Torres; Anna González-Neira; Cristobal Belda-Iniesta; Victor González-Rumayor; Blanca López-Ibor; Angel Ayuso-Sacido
Journal:  Cancers (Basel)       Date:  2019-12-25       Impact factor: 6.639

Review 10.  Clinical relevance of blood-based ctDNA analysis: mutation detection and beyond.

Authors:  Laura Keller; Yassine Belloum; Harriet Wikman; Klaus Pantel
Journal:  Br J Cancer       Date:  2020-09-24       Impact factor: 7.640
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.