Literature DB >> 30612978

Penile Stretching as a Treatment for Peyronie's Disease: A Review.

Matthew G Cowper1, Connor B Burkett1, Tan V Le2, Nickolas Scherzer1, Wayne J G Hellstrom3.   

Abstract

INTRODUCTION: Peyronie's disease (PD) is a debilitating condition that affects a sizable number of men worldwide. Current treatment options consist of oral therapy, intralesional injections, and surgery. Penile stretching has been used as a treatment for PD, including penile traction therapy (PTT) and vacuum erection devices (VEDs), with numerous trials completed or underway. AIM: To present and summarize the current literature on penile stretching for the treatment of PD.
METHODS: Using PubMed, we performed a literature review of studies from January 1990 through July 2018 that focused on penile stretching for PD management. PTT and VED were included in the search criteria. MAIN OUTCOME
METHODS: Penile curvature correction was effective, and stretched penile length was improved.
RESULTS: PD therapies that use penile stretching as a mechanical intervention to alter tissue characteristics were studied. PTT has been successful in primary penile lengthening and curvature correction in the acute phase of PD. PTT also improved length retention in men undergoing plication and incision/grafting procedures. Combination of PTT and intralesional injection therapy for PD treatment requires further investigation. There are fewer studies investigating VEDs and their role in PD management, but initial small trials suggest a role in curvature correction and penile lengthening.
CONCLUSIONS: Penile stretching is an effective therapy for PD. Data from limited trials suggest a role for PTT and VEDs in the management of PD, although further research is needed. Cowper MG, Burkett CB, Le TV et al. Penile Stretching as a Treatment for Peyronie's Disease: A Review. Sex Med Rev 2019;7:508-515.
Copyright © 2018 International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Penile Stretching; Peyronie’s Disease; Traction Therapy; Treatment; Vacuum Erection Device

Mesh:

Year:  2019        PMID: 30612978     DOI: 10.1016/j.sxmr.2018.11.002

Source DB:  PubMed          Journal:  Sex Med Rev        ISSN: 2050-0521


  4 in total

Review 1.  Conservative Therapy for Peyronie's Disease: a Contemporary Review of the Literature.

Authors:  Ayad Yousif; Caleb Natale; Wayne J G Hellstrom
Journal:  Curr Urol Rep       Date:  2021-01-08       Impact factor: 3.092

Review 2.  Indications and characteristics of penile traction and vacuum erection devices.

Authors:  Abida Sultana; Peter Grice; Josip Vukina; Ian Pearce; Vaibhav Modgil
Journal:  Nat Rev Urol       Date:  2021-11-11       Impact factor: 14.432

3.  Multiple plaque incisions with or without grafting for Peyronie's disease.

Authors:  Paul K Hegarty; Daniel O Sullivan; Penelope A Hegarty; Helen Zafirakis
Journal:  BJUI Compass       Date:  2022-01-12

4.  Intratunical injection of rat-derived bone marrow mesenchymal stem cells prevents fibrosis and is associated with increased Smad7 expression in a rat model of Peyronie's disease.

Authors:  Wenting Wang; Weifang Ding; Xuebao Zhang; Shuang Wu; Tianxi Yu; Xin Cui; Yaqi Xie; Diandong Yang; Chunhua Lin
Journal:  Stem Cell Res Ther       Date:  2022-07-30       Impact factor: 8.079

  4 in total

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