Literature DB >> 30611609

Actin Post-translational Modifications: The Cinderella of Cytoskeletal Control.

Sylvia Varland1, Joël Vandekerckhove2, Adrian Drazic3.   

Abstract

Actin is one of the most abundant proteins in eukaryotic cells and the main component of the microfilament system. It plays essential roles in numerous cellular activities, including muscle contraction, maintenance of cell integrity, and motility, as well as transcriptional regulation. Besides interacting with various actin-binding proteins (ABPs), proper actin function is regulated by post-translational modifications (PTMs), such as acetylation, arginylation, oxidation, and others. Here, we explain how actin PTMs can contribute to filament formation and stability, and may have additional actin regulatory functions, which potentially contribute to disease development.
Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.

Keywords:  N-terminal modifications; acetylation; actin; cytoskeleton; oxidation; post-translational modifications

Year:  2019        PMID： 30611609     DOI： 10.1016/j.tibs.2018.11.010

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  31 in total

Review 1.  Regulation of actin isoforms in cellular and developmental processes.

Authors:  Anna S Kashina
Journal:  Semin Cell Dev Biol       Date:  2020-01-27       Impact factor: 7.727

Review 2.  The oligodendrocyte growth cone and its actin cytoskeleton: A fundamental element for progenitor cell migration and CNS myelination.

Authors:  Elizabeth J Thomason; Miguel Escalante; Donna J Osterhout; Babette Fuss
Journal:  Glia       Date:  2019-11-07       Impact factor: 7.452

3.  The Caenorhabditis elegans ASPP homolog APE-1 is a junctional protein phosphatase 1 modulator.

Authors:  Gwendolyn M Beacham; Derek T Wei; Erika Beyrent; Ying Zhang; Jian Zheng; Mari M K Camacho; Laurence Florens; Gunther Hollopeter
Journal:  Genetics       Date:  2022-08-30       Impact factor: 4.402

4.  A solution to the long-standing problem of actin expression and purification.

Authors:  Rachel H Ceron; Peter J Carman; Grzegorz Rebowski; Malgorzata Boczkowska; Robert O Heuckeroth; Roberto Dominguez
Journal:  Proc Natl Acad Sci U S A       Date:  2022-10-05       Impact factor: 12.779

5.  Post-Translational Modifications During Brain Development.

Authors:  Bradley J Smith; Victor Corasolla Carregari
Journal:  Adv Exp Med Biol       Date:  2022       Impact factor: 3.650

6.  Known and Unexplored Post-Translational Modification Pathways in Schizophrenia.

Authors:  Bradley J Smith; Victor C Carregari
Journal:  Adv Exp Med Biol       Date:  2022       Impact factor: 3.650

7.  An actin-related protein that is most highly expressed in Drosophila testes is critical for embryonic development.

Authors:  Courtney M Schroeder; Sarah A Tomlin; Isabel Mejia Natividad; John R Valenzuela; Janet M Young; Harmit S Malik
Journal:  Elife       Date:  2021-07-20       Impact factor: 8.140

Review 8.  Oxidative Stress and Hypertension.

Authors:  Kathy K Griendling; Livia L Camargo; Francisco J Rios; Rhéure Alves-Lopes; Augusto C Montezano; Rhian M Touyz
Journal:  Circ Res       Date:  2021-04-01       Impact factor: 17.367

9.  Actin filament oxidation by MICAL1 suppresses protections from cofilin-induced disassembly.

Authors:  Hugo Wioland; Stéphane Frémont; Bérengère Guichard; Arnaud Echard; Antoine Jégou; Guillaume Romet-Lemonne
Journal:  EMBO Rep       Date:  2021-01-04       Impact factor: 8.807

10.  Acupuncture Regulates Serum Differentially Expressed Proteins in Patients with Chronic Atrophic Gastritis: A Quantitative iTRAQ Proteomics Study.

Authors:  Feng Li; Bai Yang; Yanan Liu; Tianying Tang; Cun Wang; Mei Li; Siyi Lv; Qin Qi; Huirong Liu; Zheng Shi; Huangan Wu; Xiaomei Wang
Journal:  Evid Based Complement Alternat Med       Date:  2021-06-14       Impact factor: 2.629
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