Literature DB >> 30611019

Establishment of human embryonic stem cell line Amicqui-2 using poor-quality embryos from Mexican population.

Daniela Ávila-González1, Omar Martínez-Alarcón2, Guadalupe García-López2, Néstor Emmanuel Díaz-Martínez3, Guadalupe Razo-Aguilera4, María Yolotzin Valdespino-Vázquez5, Elsa Romelia Moreno-Verduzco6, Eva Vega-Hernández7, Juan Carlos Regalado-Hernández7, Julio Francisco De la Jara-Díaz7, Anayansi Molina-Hernández2, Héctor Flores-Herrera8, Wendy Portillo9, Néstor Fabián Díaz10.   

Abstract

Although investigation with human embryonic stem cells (HESC) is not decreasing, the derivation of new lines has been diminished. The preeminence of only a few HESC lines in research is accompanied by lack of universal applicability of results as well as by genetic under-representation. We previously reported the derivation of one line with male karyotype from Mexican population. Here, we derived one HESC line (Amicqui-2) with female karyotype from poor-quality embryos. These line comply the pluripotent requirements (normal karyotype, detection of pluripotency-associated markers, mycoplasma test and teratoma formation) and could be a valuable model for studying diseases specific to under-represented population.
Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

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Year:  2018        PMID: 30611019     DOI: 10.1016/j.scr.2018.101364

Source DB:  PubMed          Journal:  Stem Cell Res        ISSN: 1873-5061            Impact factor:   2.020


  1 in total

1.  The human amniotic epithelium confers a bias to differentiate toward the neuroectoderm lineage in human embryonic stem cells.

Authors:  Daniela Ávila-González; Wendy Portillo; Carla P Barragán-Álvarez; Georgina Hernandez-Montes; Eliezer Flores-Garza; Anayansi Molina-Hernández; Néstor Emmanuel Díaz-Martínez; Néstor F Díaz
Journal:  Elife       Date:  2022-07-11       Impact factor: 8.713

  1 in total

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