Literature DB >> 30609398

Cancer Stem Cells: The Architects of the Tumor Ecosystem.

Briana C Prager1, Qi Xie2, Shideng Bao3, Jeremy N Rich4.   

Abstract

Cancer stem cells (CSCs) proactively remodel their microenvironment to maintain a supportive niche. Viewed through the lens of an ecosystem, numerous tumor components have multi-directional interactions involving CSCs, supporting the complexity of tumors to maintain growth in a dynamic host. In this Perspective, we discuss how CSCs are active architects of their microenvironment and drive interactions with other tumor components, such as immune cells, cancer-associated fibroblasts and differentiated cells, blood vessels, and other extracellular cues to engineer a sustainable niche. We also highlight considerations for modeling this dynamic tumor ecology and discuss potential therapeutic strategies for targeting these multifaceted interactions.
Copyright © 2018 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Year:  2019        PMID： 30609398      PMCID： PMC6350931          DOI： 10.1016/j.stem.2018.12.009

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  162 in total

1.  CCL2 mediates cross-talk between cancer cells and stromal fibroblasts that regulates breast cancer stem cells.

Authors:  Akihiro Tsuyada; Amy Chow; Jun Wu; George Somlo; Peiguo Chu; Sofia Loera; Thehang Luu; Arthur Xuejun Li; Xiwei Wu; Wei Ye; Shiuan Chen; Weiying Zhou; Yang Yu; Yuan-Zhong Wang; Xiubao Ren; Hui Li; Peggy Scherle; Yukio Kuroki; Shizhen Emily Wang
Journal:  Cancer Res       Date:  2012-04-03       Impact factor: 12.701

2.  A vascular niche and a VEGF-Nrp1 loop regulate the initiation and stemness of skin tumours.

Authors:  Benjamin Beck; Gregory Driessens; Steven Goossens; Khalil Kass Youssef; Anna Kuchnio; Amélie Caauwe; Panagiota A Sotiropoulou; Sonja Loges; Gaelle Lapouge; Aurélie Candi; Guilhem Mascre; Benjamin Drogat; Sophie Dekoninck; Jody J Haigh; Peter Carmeliet; Cédric Blanpain
Journal:  Nature       Date:  2011-10-19       Impact factor: 49.962

3.  Involvement of chemokine receptors in breast cancer metastasis.

Authors:  A Müller; B Homey; H Soto; N Ge; D Catron; M E Buchanan; T McClanahan; E Murphy; W Yuan; S N Wagner; J L Barrera; A Mohar; E Verástegui; A Zlotnik
Journal:  Nature       Date:  2001-03-01       Impact factor: 49.962

4.  Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation.

Authors:  Nahyun Choi; Boyu Zhang; Li Zhang; Michael Ittmann; Li Xin
Journal:  Cancer Cell       Date:  2012-02-14       Impact factor: 31.743

5.  Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression.

Authors:  Chih-Hao Chang; Jing Qiu; David O'Sullivan; Michael D Buck; Takuro Noguchi; Jonathan D Curtis; Qiongyu Chen; Mariel Gindin; Matthew M Gubin; Gerritje J W van der Windt; Elena Tonc; Robert D Schreiber; Edward J Pearce; Erika L Pearce
Journal:  Cell       Date:  2015-08-27       Impact factor: 41.582

6.  Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche.

Authors:  Haobin Ye; Biniam Adane; Nabilah Khan; Timothy Sullivan; Mohammad Minhajuddin; Maura Gasparetto; Brett Stevens; Shanshan Pei; Marlene Balys; John M Ashton; Dwight J Klemm; Carolien M Woolthuis; Alec W Stranahan; Christopher Y Park; Craig T Jordan
Journal:  Cell Stem Cell       Date:  2016-06-30       Impact factor: 24.633

7.  Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas.

Authors:  Arnout G Schepers; Hugo J Snippert; Daniel E Stange; Maaike van den Born; Johan H van Es; Marc van de Wetering; Hans Clevers
Journal:  Science       Date:  2012-08-01       Impact factor: 47.728

8.  THE METABOLISM OF TUMORS IN THE BODY.

Authors:  O Warburg; F Wind; E Negelein
Journal:  J Gen Physiol       Date:  1927-03-07       Impact factor: 4.086

9.  Impact of CD44 expression on radiation response for bladder cancer.

Authors:  Chun-Te Wu; Wei-Yu Lin; Ying-Hsu Chang; Wen-Cheng Chen; Miao-Fen Chen
Journal:  J Cancer       Date:  2017-04-09       Impact factor: 4.207

10.  A restricted cell population propagates glioblastoma growth after chemotherapy.

Authors:  Jian Chen; Yanjiao Li; Tzong-Shiue Yu; Renée M McKay; Dennis K Burns; Steven G Kernie; Luis F Parada
Journal:  Nature       Date:  2012-08-23       Impact factor: 49.962
View more
  133 in total

Review 1.  How Tumor Cell Dedifferentiation Drives Immune Evasion and Resistance to Immunotherapy.

Authors:  Jinyang Li; Ben Z Stanger
Journal:  Cancer Res       Date:  2020-06-18       Impact factor: 12.701

Review 2.  Off to a Bad Start: Cancer Initiation by Pluripotency Regulator PRDM14.

Authors:  Lauren J Tracey; Monica J Justice
Journal:  Trends Genet       Date:  2019-05-23       Impact factor: 11.639

Review 3.  Roles of mitochondria in liver cancer stem cells.

Authors:  Ching-Wen Chang; Jeng-Fan Lo; Xin Wei Wang
Journal:  Differentiation       Date:  2019-05-30       Impact factor: 3.880

Review 4.  Clonal Evolution and Epithelial Plasticity in the Emergence of AR-Independent Prostate Carcinoma.

Authors:  Sara Laudato; Ana Aparicio; Filippo G Giancotti
Journal:  Trends Cancer       Date:  2019-06-29

5.  Autophagy in breast cancer metastatic dormancy: Tumor suppressing or tumor promoting functions?

Authors:  Alyssa La Belle Flynn; William P Schiemann
Journal:  J Cancer Metastasis Treat       Date:  2019-05-14

6.  The IncRNA BORG: A novel inducer of TNBC metastasis, chemoresistance, and disease recurrence.

Authors:  Alex J Gooding; Kimberly A Parker; Saba Valadkhan; William P Schiemann
Journal:  J Cancer Metastasis Treat       Date:  2019-05-10

Review 7.  Molecular Chaperones in Cancer Stem Cells: Determinants of Stemness and Potential Targets for Antitumor Therapy.

Authors:  Alexander Kabakov; Anna Yakimova; Olga Matchuk
Journal:  Cells       Date:  2020-04-06       Impact factor: 6.600

8.  Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma.

Authors:  Aparna Bhaduri; Elizabeth Di Lullo; Diane Jung; Sören Müller; Elizabeth Erin Crouch; Carmen Sandoval Espinosa; Tomoko Ozawa; Beatriz Alvarado; Julien Spatazza; Cathryn René Cadwell; Grace Wilkins; Dmitry Velmeshev; Siyuan John Liu; Martina Malatesta; Madeline Gail Andrews; Mohammed Andres Mostajo-Radji; Eric Jinsheng Huang; Tomasz Jan Nowakowski; Daniel Amos Lim; Aaron Diaz; David Ronan Raleigh; Arnold Richard Kriegstein
Journal:  Cell Stem Cell       Date:  2020-01-02       Impact factor: 24.633

9.  Sesn3 deficiency promotes carcinogen-induced hepatocellular carcinoma via regulation of the hedgehog pathway.

Authors:  Yunjian Liu; Hyeong Geug Kim; Edward Dong; Chuanpeng Dong; Menghao Huang; Yunlong Liu; Suthat Liangpunsakul; Xiaocheng Charlie Dong
Journal:  Biochim Biophys Acta Mol Basis Dis       Date:  2019-07-24       Impact factor: 5.187

10.  Chlorotoxin-directed CAR T cells for specific and effective targeting of glioblastoma.

Authors:  Dongrui Wang; Renate Starr; Wen-Chung Chang; Brenda Aguilar; Darya Alizadeh; Sarah L Wright; Xin Yang; Alfonso Brito; Aniee Sarkissian; Julie R Ostberg; Li Li; Yanhong Shi; Margarita Gutova; Karen Aboody; Behnam Badie; Stephen J Forman; Michael E Barish; Christine E Brown
Journal:  Sci Transl Med       Date:  2020-03-04       Impact factor: 17.956
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.