Literature DB >> 30607641

Impacts of dynamic degradation on the morphological and mechanical characterisation of porous magnesium scaffold.

Amir Putra Md Saad1,2, Akbar Teguh Prakoso3, M A Sulong4,5, Hasan Basri3, Dian Agustin Wahjuningrum6, Ardiyansyah Syahrom7,8.   

Abstract

This study employs a computational approach to analyse the impact of morphological changes on the structural properties of biodegradable porous Mg subjected to a dynamic immersion test for its application as a bone scaffold. Porous Mg was immersed in a dynamic immersion test for 24, 48, and 72 h. Twelve specimens were prepared and scanned using micro-CT and then reconstructed into a 3D model for finite element analysis. The structural properties from the numerical simulation were then compared to the experimental values. Correlations between morphological parameters, structural properties, and fracture type were then made. The relative losses were observed to be in agreement with relative mass loss done experimentally. The degradation rates determined using exact (degraded) surface area at particular immersion times were on average 20% higher than the degradation rates obtained using original surface area. The dynamic degradation has significantly impacted the morphological changes of porous Mg in volume fraction, surface area, and trabecular separation, which in turn affects its structural properties and increases the immersion time.

Entities:  

Keywords:  Dynamic degradation; Dynamic immersion test; Finite element analyses; Morphological parameters; Porous magnesium

Mesh:

Substances:

Year:  2019        PMID: 30607641     DOI: 10.1007/s10237-018-01115-z

Source DB:  PubMed          Journal:  Biomech Model Mechanobiol        ISSN: 1617-7940


  3 in total

Review 1.  A review of current challenges and prospects of magnesium and its alloy for bone implant applications.

Authors:  Meysam Nasr Azadani; Abolfazl Zahedi; Oluwole Kingsley Bowoto; Bankole Ibrahim Oladapo
Journal:  Prog Biomater       Date:  2022-03-03

2.  Open-porous magnesium-based scaffolds withstand in vitro corrosion under cyclic loading: A mechanistic study.

Authors:  Roxane Bonithon; Colin Lupton; Marta Roldo; Joseph Nicholas Dunlop; Gordon William Blunn; Frank Witte; Gianluca Tozzi
Journal:  Bioact Mater       Date:  2022-04-29

Review 3.  Biologically modified implantation as therapeutic bioabsorbable materials for bone defect repair.

Authors:  Chao Li; Hongzhi Lv; Yawei Du; Wenbo Zhu; Weijie Yang; Xiumei Wang; Juan Wang; Wei Chen
Journal:  Regen Ther       Date:  2021-12-31       Impact factor: 3.419

  3 in total

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