Literature DB >> 30606273

Enhancing return to work or school after a first episode of schizophrenia: the UCLA RCT of Individual Placement and Support and Workplace Fundamentals Module training.

Keith H Nuechterlein1,2, Kenneth L Subotnik1, Joseph Ventura1, Luana R Turner1, Michael J Gitlin1, Denise Gretchen-Doorly1, Deborah R Becker3, Robert E Drake4, Charles J Wallace1, Robert P Liberman1.   

Abstract

BACKGROUND: This study evaluated in a rigorous 18-month randomized controlled trial the efficacy of an enhanced vocational intervention for helping individuals with a recent first schizophrenia episode to return to and remain in competitive work or regular schooling.
METHODS: Individual Placement and Support (IPS) was adapted to meet the goals of individuals whose goals might involve either employment or schooling. IPS was combined with a Workplace Fundamentals Module (WFM) for an enhanced, outpatient, vocational intervention. Random assignment to the enhanced integrated rehabilitation program (N = 46) was contrasted with equally intensive clinical treatment at UCLA, including social skills training groups, and conventional vocational rehabilitation by state agencies (N = 23). All patients were provided case management and psychiatric services by the same clinical team and received oral atypical antipsychotic medication.
RESULTS: The IPS-WFM combination led to 83% of patients participating in competitive employment or school in the first 6 months of intensive treatment, compared with 41% in the comparison group (p < 0.005). During the subsequent year, IPS-WFM continued to yield higher rates of schooling/employment (92% v. 60%, p < 0.03). Cumulative number of weeks of schooling and/or employment was also substantially greater with the IPS-WFM intervention (45 v. 26 weeks, p < 0.004).
CONCLUSIONS: The results clearly support the efficacy of an enhanced intervention focused on recovery of participation in normative work and school settings in the initial phase of schizophrenia, suggesting potential for prevention of disability.

Entities:  

Keywords:  (Improving Work Outcome in People with Recent-Onset Schizophrenia, NCT00203788, http://www.clinicaltrials.gov); first-episode schizophrenia; functional outcome; randomized controlled trial; supported education; supported employment; work recovery

Mesh:

Substances:

Year:  2019        PMID: 30606273      PMCID: PMC6620168          DOI: 10.1017/S0033291718003860

Source DB:  PubMed          Journal:  Psychol Med        ISSN: 0033-2917            Impact factor:   7.723


  31 in total

Review 1.  Supported employment: evidence for an evidence-based practice.

Authors:  Gary R Bond
Journal:  Psychiatr Rehabil J       Date:  2004

2.  The effectiveness of skills training for improving outcomes in supported employment.

Authors:  Kim T Mueser; Steve Aalto; Deborah R Becker; John S Ogden; Rosemarie S Wolfe; Diane Schiavo; Charles J Wallace; Haiyi Xie
Journal:  Psychiatr Serv       Date:  2005-10       Impact factor: 3.084

3.  Recognizing and responding to early psychosis: a qualitative analysis of individual narratives.

Authors:  Abigail M Judge; Sue E Estroff; Diana O Perkins; David L Penn
Journal:  Psychiatr Serv       Date:  2008-01       Impact factor: 3.084

4.  Vocational outcomes of an integrated supported employment program for individuals with persistent and severe mental illness.

Authors:  Hector W H Tsang; Ashley Chan; Alvin Wong; Robert Paul Liberman
Journal:  J Behav Ther Exp Psychiatry       Date:  2008-12-25

5.  Three year follow-up study of an integrated supported employment for individuals with severe mental illness.

Authors:  Hector W H Tsang; Kelvin M T Fung; Ada Y Leung; Sally M Y Li; W M Cheung
Journal:  Aust N Z J Psychiatry       Date:  2010-01       Impact factor: 5.744

Review 6.  Supported employment for people with severe mental illness: systematic review and meta-analysis of the international evidence.

Authors:  Matthew Modini; Leona Tan; Beate Brinchmann; Min-Jung Wang; Eoin Killackey; Nicholas Glozier; Arnstein Mykletun; Samuel B Harvey
Journal:  Br J Psychiatry       Date:  2016-04-21       Impact factor: 9.319

7.  Supported employment and education in comprehensive, integrated care for first episode psychosis: Effects on work, school, and disability income.

Authors:  Robert Rosenheck; Kim T Mueser; Kyaw Sint; Haiqun Lin; David W Lynde; Shirley M Glynn; Delbert G Robinson; Nina R Schooler; Patricia Marcy; Somaia Mohamed; John M Kane
Journal:  Schizophr Res       Date:  2016-09-23       Impact factor: 4.939

8.  An RCT Evaluating the Effects of Skills Training and Medication Type on Work Outcomes Among Patients With Schizophrenia.

Authors:  Shirley M Glynn; Stephen R Marder; Douglas L Noordsy; Christopher O'Keefe; Deborah R Becker; Robert E Drake; Catherine A Sugar
Journal:  Psychiatr Serv       Date:  2016-11-01       Impact factor: 3.084

9.  A randomized clinical trial of supported employment for inner-city patients with severe mental disorders.

Authors:  R E Drake; G J McHugo; R R Bebout; D R Becker; M Harris; G R Bond; E Quimby
Journal:  Arch Gen Psychiatry       Date:  1999-07

10.  Developmental Processes in Schizophrenic Disorders: longitudinal studies of vulnerability and stress.

Authors:  K H Nuechterlein; M E Dawson; M Gitlin; J Ventura; M J Goldstein; K S Snyder; C M Yee; J Mintz
Journal:  Schizophr Bull       Date:  1992       Impact factor: 9.306

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  11 in total

Review 1.  Systematic Review of the Impact on Return to Work of Return-to-Work Coordinators.

Authors:  M Dol; S Varatharajan; E Neiterman; E McKnight; M Crouch; E McDonald; C Malachowski; N Dali; E Giau; E MacEachen
Journal:  J Occup Rehabil       Date:  2021-04-21

2.  Supported Education and Employment Services for Young People with Early Psychosis in OnTrackNY.

Authors:  Jennifer L Humensky; Ilana Nossel; Iruma Bello; Lisa B Dixon
Journal:  J Ment Health Policy Econ       Date:  2019-09-01

3.  A Systematic Review and Meta-analysis of IPS Supported Employment for Young Adults with Mental Health Conditions.

Authors:  Gary R Bond; Monirah Al-Abdulmunem; Jessica Marbacher; Thomas N Christensen; Vigdis Sveinsdottir; Robert E Drake
Journal:  Adm Policy Ment Health       Date:  2022-10-11

Review 4.  Interventions to improve social circumstances of people with mental health conditions: a rapid evidence synthesis.

Authors:  Phoebe Barnett; Thomas Steare; Zainab Dedat; Stephen Pilling; Paul McCrone; Martin Knapp; Eleanor Cooke; Daphne Lamirel; Sarah Dawson; Peter Goldblatt; Stephani Hatch; Claire Henderson; Rachel Jenkins; T K; Karen Machin; Alan Simpson; Prisha Shah; Martin Stevens; Martin Webber; Sonia Johnson; Brynmor Lloyd-Evans
Journal:  BMC Psychiatry       Date:  2022-04-28       Impact factor: 4.144

5.  Association between cortical volume and gray-white matter contrast with second generation antipsychotic medication exposure in first episode male schizophrenia patients.

Authors:  Won Jong Chwa; Todd A Tishler; Catalina Raymond; Cathy Tran; Faizan Anwar; J Pablo Villablanca; Joseph Ventura; Kenneth L Subotnik; Keith H Nuechterlein; Benjamin M Ellingson
Journal:  Schizophr Res       Date:  2020-05-31       Impact factor: 4.939

Review 6.  Vocational Interventions to Improve Employment Participation of People with Psychosocial Disability, Autism and/or Intellectual Disability: A Systematic Review.

Authors:  Isabelle Weld-Blundell; Marissa Shields; Alexandra Devine; Helen Dickinson; Anne Kavanagh; Claudia Marck
Journal:  Int J Environ Res Public Health       Date:  2021-11-17       Impact factor: 3.390

7.  Personnel time required for supported employment and education services for individuals in a recent-onset psychosis treatment program.

Authors:  Jennifer L Humensky; Luana R Turner; Lisa B Dixon; Robert E Drake; Deborah R Becker; Kenneth L Subotnik; Joseph Ventura; Keith H Nuechterlein
Journal:  Early Interv Psychiatry       Date:  2020-04-29       Impact factor: 2.732

Review 8.  Vocational Service Models and Approaches to Improve Job Tenure of People With Severe and Enduring Mental Illness: A Narrative Review.

Authors:  Caitlin McDowell; Priscilla Ennals; Ellie Fossey
Journal:  Front Psychiatry       Date:  2021-07-09       Impact factor: 4.157

9.  The Provision of Education and Employment Support At the Outreach and Support in South London (OASIS) Service for People at Clinical High Risk for Psychosis.

Authors:  Stefania Tognin; Lara Grady; Serena Ventura; Lucia Valmaggia; Victoria Sear; Philip McGuire; Paolo Fusar-Poli; Tom J Spencer
Journal:  Front Psychiatry       Date:  2019-11-08       Impact factor: 4.157

10.  Development of a Supported Education Program for Students with Severe Mental Disorders in India.

Authors:  Sadananda Reddy Annapally; Aarti Jagannathan; Thomas Kishore; Muralidhar Daliboyina; Channaveerachari Naveen Kumar
Journal:  Indian J Psychol Med       Date:  2020-12-08
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