| Literature DB >> 30605130 |
Rana Ashkar1, Hassina Z Bilheux2, Heliosa Bordallo3, Robert Briber4, David J E Callaway5, Xiaolin Cheng6, Xiang Qiang Chu7, Joseph E Curtis8, Mark Dadmun9, Paul Fenimore10, David Fushman11, Frank Gabel12, Kushol Gupta13, Frederick Herberle2, Frank Heinrich8, Liang Hong14, John Katsaras15, Zvi Kelman16, Eugenia Kharlampieva17, Gerald R Kneller18, Andrey Kovalevsky19, Susan Krueger8, Paul Langan2, Raquel Lieberman20, Yun Liu8, Mathias Losche21, Edward Lyman22, Yimin Mao8, John Marino16, Carla Mattos23, Flora Meilleur2, Peter Moody24, Jonathan D Nickels1, William B O'Dell16, Hugh O'Neill2, Ursula Perez-Salas2, Judith Peters3, Loukas Petridis4, Alexei P Sokolov9, Christopher Stanley2, Norman Wagner5, Michael Weinrich8, Kevin Weiss2, Troy Wymore7, Yang Zhang8, Jeremy C Smith6.
Abstract
The scattering of neutrons can be used to provide information on the structure and dynamics of biological systems on multiple length and time scales. Pursuant to a National Science Foundation-funded workshop in February 2018, recent developments in this field are reviewed here, as well as future prospects that can be expected given recent advances in sources, instrumentation and computational power and methods. Crystallography, solution scattering, dynamics, membranes, labeling and imaging are examined. For the extraction of maximum information, the incorporation of judicious specific deuterium labeling, the integration of several types of experiment, and interpretation using high-performance computer simulation models are often found to be particularly powerful.Entities:
Keywords: biological systems; neutron scattering; structure and dynamics
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Year: 2018 PMID： 30605130 DOI： 10.1107/S2059798318017503
Source DB: PubMed Journal: Acta Crystallogr D Struct Biol ISSN： 2059-7983 Impact factor: 7.652