Literature DB >> 30602937

Bridging trees for posterior inference on ancestral recombination graphs.

K Heine1, A Beskos2, A Jasra3, D Balding4,5, M De Iorio2,6.   

Abstract

We present a new Markov chain Monte Carlo algorithm, implemented in the software Arbores, for inferring the history of a sample of DNA sequences. Our principal innovation is a bridging procedure, previously applied only for simple stochastic processes, in which the local computations within a bridge can proceed independently of the rest of the DNA sequence, facilitating large-scale parallelization.

Keywords:  Bayesian inference; Markov chain Monte Carlo; ancestral recombination graph; coalescent; tree scanning

Year:  2018        PMID: 30602937      PMCID: PMC6304023          DOI: 10.1098/rspa.2018.0568

Source DB:  PubMed          Journal:  Proc Math Phys Eng Sci        ISSN: 1364-5021            Impact factor:   2.704


  2 in total

Review 1.  Methodologies for Microbial Ancestral Sequence Reconstruction.

Authors:  Miguel Arenas
Journal:  Methods Mol Biol       Date:  2022

2.  Bayesian inference of ancestral recombination graphs.

Authors:  Ali Mahmoudi; Jere Koskela; Jerome Kelleher; Yao-Ban Chan; David Balding
Journal:  PLoS Comput Biol       Date:  2022-03-09       Impact factor: 4.475

  2 in total

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