| Literature DB >> 30602937 |
K Heine1, A Beskos2, A Jasra3, D Balding4,5, M De Iorio2,6.
Abstract
We present a new Markov chain Monte Carlo algorithm, implemented in the software Arbores, for inferring the history of a sample of DNA sequences. Our principal innovation is a bridging procedure, previously applied only for simple stochastic processes, in which the local computations within a bridge can proceed independently of the rest of the DNA sequence, facilitating large-scale parallelization.Keywords: Bayesian inference; Markov chain Monte Carlo; ancestral recombination graph; coalescent; tree scanning
Year: 2018 PMID: 30602937 PMCID: PMC6304023 DOI: 10.1098/rspa.2018.0568
Source DB: PubMed Journal: Proc Math Phys Eng Sci ISSN: 1364-5021 Impact factor: 2.704