Literature DB >> 30601234

Can a Cohesive Silicone Bandage Outperform an Adhesive Silicone Gel Sheet in the Treatment of Scars? A Randomized Comparative Trial.

Peter Moortgat1, Jill Meirte1, Koen Maertens1, Cynthia Lafaire1, Lieve De Cuyper1, Mieke Anthonissen1.   

Abstract

BACKGROUND: The use of topical silicone to treat scars is widespread, and various studies have demonstrated its efficacy to treat scars. A new form of silicone application is a cohesive elastic bandage. The aim of this study was to compare the effects of this bandage versus an adhesive silicone gel sheet on scar elasticity after burn injury.
METHODS: A total of 60 patients were enrolled in a randomized, prospective, single-blind, single-center, comparative, parallel-group study. The participants were assigned randomly to one of two treatment arms: one for treatment with a cohesive silicone bandage, and the other with a silicone gel sheet. The color was measured objectively using a Chromameter, and the Cutometer was used to assess vertical elasticity. For subjective assessment of the scars, the authors used the Patient and Observer Scar Assessment Scale.
RESULTS: The results reveal that there were no significant differences between the two interventions for most subjective assessments and color measurements. However, the group that received treatment with the cohesive silicone bandage did seem to perform statistically significantly better than the silicone gel sheet group for vertical elasticity and the global score of the Patient and Observer Scar Assessment Scale (observer scale). This was probably because of the unique microstructure of the bandage that ensured a standardized pressure together with uninterrupted contact with the skin.
CONCLUSIONS: An elastic cohesive silicone bandage seems to outperform silicone gel sheets for vertical elasticity when treating hypertrophic burn scars. The authors recommend including timing of application and duration of application in future studies. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, II.

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Year:  2019        PMID: 30601234     DOI: 10.1097/PRS.0000000000005369

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN: 0032-1052            Impact factor:   4.730


  5 in total

Review 1.  Silicone gel sheeting for treating hypertrophic scars.

Authors:  Qingling Jiang; Junjie Chen; Fan Tian; Zhenmi Liu
Journal:  Cochrane Database Syst Rev       Date:  2021-09-26

2.  Evaluation of an International Classification of Functioning, Disability and Health-based rehabilitation for thermal burn injuries: a prospective non-randomized design.

Authors:  Hubert Neubauer; Annette Stolle; Sabine Ripper; Felix Klimitz; Hans Ziegenthaler; Mareike Strupat; Ulrich Kneser; Leila Harhaus
Journal:  Trials       Date:  2019-12-19       Impact factor: 2.279

Review 3.  Evidence-based therapy in hypertrophic scars: An update of a systematic review.

Authors:  Sebastian P Nischwitz; Katharina Rauch; Hanna Luze; Elisabeth Hofmann; Alexander Draschl; Petra Kotzbeck; Lars-Peter Kamolz
Journal:  Wound Repair Regen       Date:  2020-06-15       Impact factor: 3.617

4.  Case study: Pilot testing of a local acupuncture intervention protocol for burn scars.

Authors:  Catherine R Tuckey; Susan H Kohut; Dale W Edgar
Journal:  Scars Burn Heal       Date:  2022-02-23

5.  HDAC5-mediated Smad7 silencing through MEF2A is critical for fibroblast activation and hypertrophic scar formation.

Authors:  Ya Gao; Yangdan Liu; Danning Zheng; Chiakang Ho; Dongsheng Wen; Jiaming Sun; Lu Huang; Yuxin Liu; Qingfeng Li; Yifan Zhang
Journal:  Int J Biol Sci       Date:  2022-09-11       Impact factor: 10.750

  5 in total

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