| Literature DB >> 30600322 |
Abstract
Evaluation of microsatellite instability (MSI) of every colorectal cancer (CRC) is important for prognostic and therapeutic purposes, while molecular testing helps identify actionable targeted therapy for patients with metastatic disease. This review will discuss the biomarkers commonly encountered in the clinical evaluation of CRC, and practical issues regarding MSI screening, reporting, interpretation, molecular test indication, and specimen requirements.Entities:
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Year: 2019 PMID: 30600322 DOI: 10.1038/s41379-018-0136-1
Source DB: PubMed Journal: Mod Pathol ISSN: 0893-3952 Impact factor: 7.842