Literature DB >> 3060009

Stress proteins and the immune response to mycobacteria--antigens as virulence factors?

D B Young1, A Mehlert, V Bal, P Mendez-Samperio, J Ivanyi, J R Lamb.   

Abstract

The immune response to mycobacterial infection includes pathogenic as well as protective activities. It is possible that different types of immune responses are associated with recognition of different antigenic determinants. Amongst the antigens which are prominent in antibody and T cell recognition of mycobacteria, we have identified members of highly conserved stress protein families. Mapping of antigenic determinants on stress proteins shows that both species-specific and conserved regions of these proteins can take part in immune recognition. Induction of an immune response to conserved, "self-like", determinants on stress proteins could play a role in the immunopathology associated with chronic mycobacterial infections.

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Year:  1988        PMID： 3060009     DOI： 10.1007/bf00461861

Source DB:  PubMed          Journal:  Antonie Van Leeuwenhoek        ISSN： 0003-6072            Impact factor:   2.271


  35 in total

1.  The relation between major histocompatibility complex (MHC) restriction and the capacity of Ia to bind immunogenic peptides.

Authors:  S Buus; A Sette; S M Colon; C Miles; H M Grey
Journal:  Science       Date:  1987-03-13       Impact factor: 47.728

2.  Efficient mapping of protein antigenic determinants.

Authors:  V Mehra; D Sweetser; R A Young
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

3.  Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis.

Authors:  W van Eden; J E Thole; R van der Zee; A Noordzij; J D van Embden; E J Hensen; I R Cohen
Journal:  Nature       Date:  1988-01-14       Impact factor: 49.962

Review 4.  Cloned antigen genes of Brugia filarial parasites.

Authors:  M E Selkirk; P J Rutherford; D a Denham; F Partono; R M Maizels
Journal:  Biochem Soc Symp       Date:  1987

5.  The Mycobacterium tuberculosis 65-kilodalton antigen is a heat shock protein which corresponds to common antigen and to the Escherichia coli GroEL protein.

Authors:  T M Shinnick; M H Vodkin; J C Williams
Journal:  Infect Immun       Date:  1988-02       Impact factor: 3.441

6.  Homologous plant and bacterial proteins chaperone oligomeric protein assembly.

Authors:  S M Hemmingsen; C Woolford; S M van der Vies; K Tilly; D T Dennis; C P Georgopoulos; R W Hendrix; R J Ellis
Journal:  Nature       Date:  1988-05-26       Impact factor: 49.962

7.  A heat shock operon in Coxiella burnetti produces a major antigen homologous to a protein in both mycobacteria and Escherichia coli.

Authors:  M H Vodkin; J C Williams
Journal:  J Bacteriol       Date:  1988-03       Impact factor: 3.490

8.  Immunological evaluation of a component isolated from Mycobacterium bovis BCG with a monoclonal antibody to M. bovis BCG.

Authors:  P Minden; P J Kelleher; J H Freed; L D Nielsen; P J Brennan; L McPheron; J K McClatchy
Journal:  Infect Immun       Date:  1984-11       Impact factor: 3.441

9.  Stress proteins are immune targets in leprosy and tuberculosis.

Authors:  D Young; R Lathigra; R Hendrix; D Sweetser; R A Young
Journal:  Proc Natl Acad Sci U S A       Date:  1988-06       Impact factor: 11.205

10.  A major immunogen in Schistosoma mansoni infections is homologous to the heat-shock protein Hsp70.

Authors:  R Hedstrom; J Culpepper; R A Harrison; N Agabian; G Newport
Journal:  J Exp Med       Date:  1987-05-01       Impact factor: 14.307
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  8 in total

Review 1.  The role of BCG vaccine in tuberculosis control.

Authors:  M Gheorghiu
Journal:  Indian J Pediatr       Date:  1990 Sep-Oct       Impact factor: 1.967

2.  Dynamics of the phagocytic cell response within the lungs of parabiotic mice infected with mycobacteria with decreasing virulence for mice.

Authors:  F M Collins
Journal:  Infect Immun       Date:  1990-07       Impact factor: 3.441

Review 3.  The humoral immune response to heat shock proteins.

Authors:  J Mollenhauer; A Schulmeister
Journal:  Experientia       Date:  1992-07-15

4.  Mycobacterium tuberculosis expresses two chaperonin-60 homologs.

Authors:  T H Kong; A R Coates; P D Butcher; C J Hickman; T M Shinnick
Journal:  Proc Natl Acad Sci U S A       Date:  1993-04-01       Impact factor: 11.205

5.  Investigations on etiology of Crohn's disease. Humoral immune response to stress (heat shock) proteins.

Authors:  D C Markesich; E T Sawai; J S Butel; D Y Graham
Journal:  Dig Dis Sci       Date:  1991-04       Impact factor: 3.199

6.  Antigen-coated latex particles as a model system for probing monocyte responses in leprosy.

Authors:  R S Hasan; H M Dockrell; S Jamil; T J Chiang; R Hussain
Journal:  Infect Immun       Date:  1993-09       Impact factor: 3.441

7.  H(2)O(2), which causes macrophage-related stress, triggers induction of expression of virulence-associated plasmid determinants in Rhodococcus equi.

Authors:  Stephanie Benoit; Abdellah Benachour; Said Taouji; Yanick Auffray; Axel Hartke
Journal:  Infect Immun       Date:  2002-07       Impact factor: 3.441

Review 8.  BCG vaccination in India and tuberculosis in children: newer facets.

Authors:  P M Udani
Journal:  Indian J Pediatr       Date:  1994 Sep-Oct       Impact factor: 1.967
  8 in total

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