Literature DB >> 30590603

Haemophilus-Dominant Nasopharyngeal Microbiota Is Associated With Delayed Clearance of Respiratory Syncytial Virus in Infants Hospitalized for Bronchiolitis.

Jonathan M Mansbach1, Kohei Hasegawa2, Pedro A Piedra3,4, Vasanthi Avadhanula3, Joseph F Petrosino5,3, Ashley F Sullivan2, Janice A Espinola2, Carlos A Camargo2.   

Abstract

The relation of nasopharyngeal microbiota to the clearance of respiratory syncytial virus (RSV) in infants hospitalized for bronchiolitis is not known. In a multicenter cohort, we found that 106 of 557 infants (19%) hospitalized with RSV bronchiolitis had the same RSV subtype 3 weeks later (ie, delayed clearance of RSV). Using 16S ribosomal RNA gene sequencing and a clustering approach, infants with a Haemophilus-dominant microbiota profile at hospitalization were more likely than those with a mixed profile to have delayed clearance, after adjustment for 11 factors, including viral load. Nasopharyngeal microbiota composition is associated with delayed RSV clearance.
© The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  Airway microbiota; bronchiolitis; children; infant; microbiome; respiratory infection; respiratory syncytial virus

Mesh：

Year:  2019        PMID： 30590603      PMCID： PMC6500556          DOI： 10.1093/infdis/jiy741

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


  15 in total

1.  Prospective multicenter study of viral etiology and hospital length of stay in children with severe bronchiolitis.

Authors:  Jonathan M Mansbach; Pedro A Piedra; Stephen J Teach; Ashley F Sullivan; Tate Forgey; Sunday Clark; Janice A Espinola; Carlos A Camargo
Journal:  Arch Pediatr Adolesc Med       Date:  2012-08

2.  Prolonged viral replication and longitudinal viral dynamic differences among respiratory syncytial virus infected infants.

Authors:  Monica E Brint; Joshua M Hughes; Aditya Shah; Chelsea R Miller; Lisa G Harrison; Elizabeth A Meals; Jacqueline Blanch; Charlotte R Thompson; Stephania A Cormier; John P DeVincenzo
Journal:  Pediatr Res       Date:  2017-08-09       Impact factor: 3.756

3.  Nasopharyngeal Microbiota, Host Transcriptome, and Disease Severity in Children with Respiratory Syncytial Virus Infection.

Authors:  Wouter A A de Steenhuijsen Piters; Santtu Heinonen; Raiza Hasrat; Eleonora Bunsow; Bennett Smith; Maria-Carmen Suarez-Arrabal; Damien Chaussabel; Daniel M Cohen; Elisabeth A M Sanders; Octavio Ramilo; Debby Bogaert; Asuncion Mejias
Journal:  Am J Respir Crit Care Med       Date:  2016-11-01       Impact factor: 21.405

4.  Pathogenic bacteria colonizing the airways in asymptomatic neonates stimulates topical inflammatory mediator release.

Authors:  Nilofar V Følsgaard; Susanne Schjørring; Bo L Chawes; Morten A Rasmussen; Karen A Krogfelt; Susanne Brix; Hans Bisgaard
Journal:  Am J Respir Crit Care Med       Date:  2013-01-31       Impact factor: 21.405

5.  Respiratory syncytial virus infections in infants: quantitation and duration of shedding.

Authors:  C B Hall; R G Douglas; J M Geiman
Journal:  J Pediatr       Date:  1976-07       Impact factor: 4.406

6.  Towards an ecology of the lung: new conceptual models of pulmonary microbiology and pneumonia pathogenesis.

Authors:  Robert P Dickson; John R Erb-Downward; Gary B Huffnagle
Journal:  Lancet Respir Med       Date:  2014-03       Impact factor: 30.700

7.  The infant nasopharyngeal microbiome impacts severity of lower respiratory infection and risk of asthma development.

Authors:  Shu Mei Teo; Danny Mok; Kym Pham; Merci Kusel; Michael Serralha; Niamh Troy; Barbara J Holt; Belinda J Hales; Michael L Walker; Elysia Hollams; Yury A Bochkov; Kristine Grindle; Sebastian L Johnston; James E Gern; Peter D Sly; Patrick G Holt; Kathryn E Holt; Michael Inouye
Journal:  Cell Host Microbe       Date:  2015-04-09       Impact factor: 21.023

8.  The association between anterior nares and nasopharyngeal microbiota in infants hospitalized for bronchiolitis.

Authors:  Pamela N Luna; Kohei Hasegawa; Nadim J Ajami; Janice A Espinola; David M Henke; Joseph F Petrosino; Pedro A Piedra; Ashley F Sullivan; Carlos A Camargo; Chad A Shaw; Jonathan M Mansbach
Journal:  Microbiome       Date:  2018-01-03       Impact factor: 14.650

Review 9.  Neutrophils in respiratory syncytial virus infection: A target for asthma prevention.

Authors:  Ruben J Geerdink; Janesh Pillay; Linde Meyaard; Louis Bont
Journal:  J Allergy Clin Immunol       Date:  2015-08-12       Impact factor: 10.793

Review 10.  Cytokines and CD8 T cell immunity during respiratory syncytial virus infection.

Authors:  Megan E Schmidt; Steven M Varga
Journal:  Cytokine       Date:  2018-07-18       Impact factor: 3.861
View more
  9 in total

1.  Nasopharyngeal Codetection of Haemophilus influenzae and Streptococcus pneumoniae Shapes Respiratory Syncytial Virus Disease Outcomes in Children.

Authors:  Alejandro Diaz-Diaz; Eleonora Bunsow; Cristina Garcia-Maurino; Melissa Moore-Clingenpeel; Jeffrey Naples; Alexis Juergensen; Sara Mertz; Huanyu Wang; Amy L Leber; James Gern; Mark W Hall; Daniel M Cohen; Octavio Ramilo; Asuncion Mejias
Journal:  J Infect Dis       Date:  2022-03-02       Impact factor: 7.759

2.  Upper respiratory tract bacterial-immune interactions during respiratory syncytial virus infection in infancy.

Authors:  Christian Rosas-Salazar; Zheng-Zheng Tang; Meghan H Shilts; Kedir N Turi; Qilin Hong; Derek A Wiggins; Christian E Lynch; Tebeb Gebretsadik; James D Chappell; R Stokes Peebles; Larry J Anderson; Suman R Das; Tina V Hartert
Journal:  J Allergy Clin Immunol       Date:  2021-09-14       Impact factor: 14.290

Review 3.  Ecological interactions in asthma: from environment to microbiota and immune responses.

Authors:  Ariangela Kozik; Yvonne J Huang
Journal:  Curr Opin Pulm Med       Date:  2020-01       Impact factor: 2.868

4.  Association of Serum Albumin With Apnea in Infants With Bronchiolitis: A Secondary Analysis of Data From the MARC-35 Study.

Authors:  Jonathan M Mansbach; Ruth J Geller; Kohei Hasegawa; Janice A Espinola; Michelle D Stevenson; Ashley F Sullivan; Carlos A Camargo
Journal:  JAMA Netw Open       Date:  2019-07-03

5.  Increased Moraxella and Streptococcus species abundance after severe bronchiolitis is associated with recurrent wheezing.

Authors:  Jonathan M Mansbach; Pamela N Luna; Chad A Shaw; Kohei Hasegawa; Joseph F Petrosino; Pedro A Piedra; Ashley F Sullivan; Janice A Espinola; Christopher J Stewart; Carlos A Camargo
Journal:  J Allergy Clin Immunol       Date:  2019-11-15       Impact factor: 10.793

6.  Transient Neutropenia in Immunocompetent Infants with Respiratory Syncytial Virus Infection.

Authors:  Tatsuya Korematsu; Hiroshi Koga
Journal:  Viruses       Date:  2021-02-15       Impact factor: 5.048

7.  Effect of Bifidobacterium animalis spp. lactis Bl-04 on Rhinovirus-Induced Colds: A Randomized, Placebo-Controlled, Single-Center, Phase II Trial in Healthy Volunteers.

Authors:  Ronald B Turner; Liisa Lehtoranta; Ashley Hibberd; Sofia Männikkö; Bryan Zabel; Nicholas Yeung; Teppo Huttunen; Frank R Burns; Markus J Lehtinen
Journal:  EClinicalMedicine       Date:  2021-12-03

Review 8.  Early-Life Lung and Gut Microbiota Development and Respiratory Syncytial Virus Infection.

Authors:  Kazuma Yagi; Nobuhiro Asai; Gary B Huffnagle; Nicholas W Lukacs; Wendy Fonseca
Journal:  Front Immunol       Date:  2022-04-04       Impact factor: 8.786

Review 9.  The Microbiome of the Nose-Friend or Foe?

Authors:  Sofia Dimitri-Pinheiro; Raquel Soares; Pedro Barata
Journal:  Allergy Rhinol (Providence)       Date:  2020-03-13
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.