Literature DB >> 30587626

Prognostic Value of Red Blood Cell Distribution Width in Non-small Cell Lung Cancer Treated With Anti-programmed Cell Death-1 Antibody.

Tatsunori Kiriu1, Masatsugu Yamamoto2, Tatsuya Nagano1, Kiyoko Koyama1, Masahiro Katsurada1, Daisuke Tamura1, Kyosuke Nakata1, Motoko Tachihara1, Kazuyuki Kobayashi1, Yoshihiro Nishimura1.   

Abstract

BACKGROUND/AIM: Red cell distribution width (RDW) has been reported to reflect the inflammation and nutrition status and predict prognosis of non-small cell lung cancer (NSCLC) patients treated with anti-programmed cell death-1 (PD-1) antibody. The aim of this study was to analyze the correlation between RDW and prognosis of NSCLC patients. PATIENTS AND METHODS: We collected retrospective data on consecutive NSCLC patients treated with anti-PD-1 antibody from December 2015 to April 2018 at the Kobe University Hospital, Japan.
RESULTS: Forty-seven patients were treated. Patients with RDW ≥16% had a significantly shorter OS (p=0.010) compared to those with RDW <16%. In multivariate analysis, RDW ≥16% was an independent factor predicting poor prognosis (p=0.019).
CONCLUSION: Pre-treatment RDW ≥16% is an indicator of poor prognosis. RDW is an inexpensive, convenient, and routinely available marker of prognosis. Copyright
© 2019, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Entities:  

Keywords:  Red blood cell distribution width; anti-programmed cell death-1 antibody; neutrophil-to-lymphocyte ratio; non-small cell lung cancer; prognostic marker

Mesh：

Substances：

Year:  2019        PMID： 30587626      PMCID： PMC6364053          DOI： 10.21873/invivo.11462

Source DB:  PubMed          Journal:  In Vivo        ISSN： 0258-851X            Impact factor:   2.155


  9 in total

1.  Immunological Microenvironment Predicts the Survival of the Patients with Hepatocellular Carcinoma Treated with Anti-PD-1 Antibody.

Authors:  Masahiro Morita; Naoshi Nishida; Kazuko Sakai; Tomoko Aoki; Hirokazu Chishina; Masahiro Takita; Hiroshi Ida; Satoru Hagiwara; Yasunori Minami; Kazuomi Ueshima; Kazuto Nishio; Yukari Kobayashi; Kazuhiro Kakimi; Masatoshi Kudo
Journal:  Liver Cancer       Date:  2021-06-09       Impact factor: 11.740

2.  Prognostic role of pretreatment neutrophil-to-lymphocyte ratio in non-small cell lung cancer patients treated with systemic therapy: a meta-analysis.

Authors:  Zimu Wang; Ping Zhan; Yanling Lv; Kaikai Shen; Yuqing Wei; Hongbing Liu; Yong Song
Journal:  Transl Lung Cancer Res       Date:  2019-06

3.  The association between RDW and survival of patients with squamous cell carcinoma of the tongue. Simple, cheap and convenient?

Authors:  Marcin Miszczyk; Iwona Jabłońska; Łukasz Magrowski; Oliwia Masri; Paweł Rajwa
Journal:  Rep Pract Oncol Radiother       Date:  2020-04-19

4.  Prognostic Significance of Preoperative Systemic Cellular Inflammatory Markers in Gliomas: A Systematic Review and Meta-Analysis.

Authors:  Da-Peng Wang; Kai Kang; Qi Lin; Jian Hai
Journal:  Clin Transl Sci       Date:  2019-10-30       Impact factor: 4.689

5.  Prognostic effect of preoperative red cell distribution width on the survival of patients who have undergone surgery for non-small cell lung cancer.

Authors:  Hiroshi Matsui; Yohei Taniguchi; Natsumi Maru; Takahiro Utsumi; Tomohito Saito; Haruaki Hino; Tomohiro Murakawa
Journal:  Mol Clin Oncol       Date:  2021-03-20

6.  Red cell distribution width as a predictor for bronchopulmonary dysplasia in premature infants.

Authors:  Hayato Go; Hitoshi Ohto; Kenneth E Nollet; Kenichi Sato; Hirotaka Ichikawa; Yohei Kume; Yuji Kanai; Hajime Maeda; Nozomi Kashiwabara; Kei Ogasawara; Maki Sato; Koichi Hashimoto; Mitsuaki Hosoya
Journal:  Sci Rep       Date:  2021-03-31       Impact factor: 4.379

7.  Acute Phase Proteins as Early Predictors for Immunotherapy Response in Advanced NSCLC: An Explorative Study.

Authors:  Marc A Schneider; Adriana Rozy; Sabine Wrenger; Petros Christopoulos; Thomas Muley; Michael Thomas; Michael Meister; Tobias Welte; Joanna Chorostowska-Wynimko; Sabina Janciauskiene
Journal:  Front Oncol       Date:  2022-01-31       Impact factor: 6.244

8.  Hematological factors associated with immunity, inflammation, and metabolism in patients with systemic lupus erythematosus: Data from a Zhuang cohort in Southwest China.

Authors:  Xiaoxia Lao; Liping Ma; Qingwei Ma; Qiaorong Ma; Zhige Yang; Lingxiao Guo; Wenzheng Nong
Journal:  J Clin Lab Anal       Date:  2020-01-24       Impact factor: 2.352

9.  Prognostic Value of the post-operative Red Blood Cell Distribution Width in rectal cancer patients with neoadjuvant chemoradiation followed surgery.

Authors:  Yingkun Ren; Zhiling Wang; Jianguo Xie; Peijun Wang
Journal:  Biosci Rep       Date:  2020-11-03       Impact factor: 3.840
  9 in total

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