Literature DB >> 30583804

Tackling Cancer with Yeast-Based Technologies.

Raphael Ferreira1, Angelo Limeta2, Jens Nielsen3.   

Abstract

The ability to precisely engineer yeast, coupled with its genetic and metabolic similarity to tumor cells, has enabled researchers to use this organism in cancer research. Here we review advances that leveraged yeast as a model organism for studying cancer biology, including the investigation of tumorigenic mechanisms, development of advanced technologies for drug discovery, production of anticancer drugs on an industrial scale, and delivering the next generation of immunotherapies.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  CRISPR; SGA; cancer vaccines; humanized antibody; immunotherapy; metabolic engineering

Mesh：

Substances：

Year:  2018        PMID： 30583804     DOI： 10.1016/j.tibtech.2018.11.013

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN： 0167-7799            Impact factor:   19.536


  7 in total

1.  Profilin choreographs actin and microtubules in cells and cancer.

Authors:  Morgan L Pimm; Jessica Hotaling; Jessica L Henty-Ridilla
Journal:  Int Rev Cell Mol Biol       Date:  2020-07-16       Impact factor: 6.813

Review 2.  Beyond tradition and convention: benefits of non-traditional model organisms in cancer research.

Authors:  Rebecca M Harman; Sanjna P Das; Arianna P Bartlett; Gat Rauner; Leanne R Donahue; Gerlinde R Van de Walle
Journal:  Cancer Metastasis Rev       Date:  2020-10-28       Impact factor: 9.264

Review 3.  Komagataella phaffii as Emerging Model Organism in Fundamental Research.

Authors:  Lukas Bernauer; Astrid Radkohl; Leonie Gabriela Katharina Lehmayer; Anita Emmerstorfer-Augustin
Journal:  Front Microbiol       Date:  2021-01-11       Impact factor: 5.640

Review 4.  Genome-scale modeling of yeast metabolism: retrospectives and perspectives.

Authors:  Yu Chen; Feiran Li; Jens Nielsen
Journal:  FEMS Yeast Res       Date:  2022-02-22       Impact factor: 2.796

5.  A hundred spotlights on microbiology: how microorganisms shape our lives.

Authors:  Didac Carmona-Gutierrez; Katharina Kainz; Andreas Zimmermann; Sebastian J Hofer; Maria A Bauer; Christoph Ruckenstuhl; Guido Kroemer; Frank Madeo
Journal:  Microb Cell       Date:  2022-04-04

6.  Label-free viability assay using in-line holographic video microscopy.

Authors:  Rostislav Boltyanskiy; Mary Ann Odete; Fook Chiong Cheong; Laura A Philips
Journal:  Sci Rep       Date:  2022-07-26       Impact factor: 4.996

7.  Fungal Dysbiosis and Intestinal Inflammation in Children With Beta-Cell Autoimmunity.

Authors:  Jarno Honkanen; Arja Vuorela; Daniel Muthas; Laura Orivuori; Kristiina Luopajärvi; Mysore Vishakante Gowda Tejesvi; Anton Lavrinienko; Anna Maria Pirttilä; Christopher L Fogarty; Taina Härkönen; Jorma Ilonen; Terhi Ruohtula; Mikael Knip; Janne J Koskimäki; Outi Vaarala
Journal:  Front Immunol       Date:  2020-03-19       Impact factor: 7.561
  7 in total

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